Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13610019 | 0.90 | KDM4E (0.56) | MEN1KDM4EALDH1A1HSD17B10USP2 | |
| SCHEMBL28518352 | 0.84 | ALDH1A1 (0.74) | MEN1KDM4EALDH1A1HSD17B10USP2 | |
| SCHEMBL13121248 | 0.80 | MEN1 (0.52) | MEN1KDM4EALDH1A1HSD17B10USP2 | |
| SCHEMBL14267652 | 0.76 | MAPT (0.56) | MEN1KDM4EALDH1A1HSD17B10USP2 | |
| SCHEMBL12790100 | 0.74 | MEN1 (1.00) | MEN1KDM4EALDH1A1HSD17B10USP2 | |
| SCHEMBL13602864 | 0.74 | CYP1A2 (0.60) | MEN1KDM4EALDH1A1HSD17B10USP2 | |
| SCHEMBL13610022 | 0.74 | MEN1 (0.46) | MEN1KDM4EALDH1A1HSD17B10USP2 | |
| SCHEMBL14950924 | 0.74 | MEN1 (0.69) | MEN1KDM4EALDH1A1HSD17B10USP2 | |
| SCHEMBL13602810 | 0.73 | MEN1 (0.80) | MEN1KDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL4298838 | 0.72 | MEN1 (0.69) | MEN1KDM4EALDH1A1HSD17B10USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1346993-B1 | LACTAM COMPOUNDS AND MEDICAL USE THEREOF | AJINOMOTO KK (JP) | 2009-10-21 | — | — | EP | disclosed |