Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13602864 | 0.90 | CYP1A2 (0.60) | MAPTKDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL13610022 | 0.90 | MEN1 (0.46) | MAPTKDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL29820174 | 0.76 | BRD4 (0.43) | MAPTKDM4EMEN1KMT2AGAA | |
| SCHEMBL13655506 | 0.76 | MEN1 (0.58) | MAPTKDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL13610019 | 0.75 | KDM4E (0.56) | MAPTKDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL13602866 | 0.75 | KDM4E (0.56) | MAPTKDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL13602795 | 0.72 | MEN1 (1.00) | MAPTKDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL13602802 | 0.68 | KMT2A (0.59) | MAPTKDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL14267665 | 0.68 | KDM4E (0.54) | MAPTKDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL13602798 | 0.68 | KDM4E (0.42) | MAPTKDM4EMEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7326701-B2 | Lactam compounds and pharmaceutical use thereof | AJINOMOTO CO., INC. (JP) | 2008-02-05 | — | — | US | disclosed |