Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.56 |
| ▸ | EDNRA | P25101 | 6/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.52 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.52 |
| ▸ | GBA1 | P04062 | 3/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | GLB1 | P16278 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13598768 | 0.93 | HDAC4 (0.59) | HDAC4HDAC10HDAC6HDAC5EDNRA | |
| SCHEMBL4139459 | 0.83 | HDAC4 (0.75) | HDAC4HDAC10HDAC6HDAC5EDNRA | |
| SCHEMBL4126957 | 0.83 | HDAC4 (0.71) | HDAC4HDAC10HDAC6HDAC5EDNRA | |
| SCHEMBL10002025 | 0.81 | HDAC4 (0.62) | HDAC4HDAC10HDAC6HDAC5EDNRA | |
| SCHEMBL4142506 | 0.81 | HDAC4 (0.77) | HDAC4HDAC10HDAC6HDAC5EDNRA | |
| SCHEMBL572629 | 0.80 | HDAC4 (0.65) | HDAC4HDAC10HDAC6HDAC5EDNRA | |
| SCHEMBL1577877 | 0.80 | HDAC4 (0.61) | HDAC4HDAC10HDAC6HDAC5EDNRA | |
| SCHEMBL2639212 | 0.80 | HDAC4 (0.61) | HDAC4HDAC10HDAC6HDAC5EDNRA | |
| SCHEMBL21597956 | 0.80 | CYP3A4 (0.57) | F2PRSS1PRSS2PRSS3GBA1 | |
| SCHEMBL2639209 | 0.80 | HDAC4 (0.61) | HDAC4HDAC10HDAC6HDAC5EDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3980057-A1 | METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STXB) MONOMERS AND OLIGOMERS, AND USES THEREOF | Institut Curie (FR) | 2022-04-13 | — | — | EP | disclosed |
| US-20210172948-A1 | METHOD FOR DETECTING BACTERIA ACCORDING TO THE GRAM SIGNAL THEREOF IN A COMPLEX SAMPLE | MAAT PHARMA (FR) | 2021-06-10 | — | — | US | disclosed |
| EP-3807416-A1 | METHOD FOR DETECTING BACTERIA ACCORDING TO THE GRAM SIGNAL THEREOF IN A COMPLEX SAMPLE | Maat Pharma (FR) | 2021-04-21 | — | — | EP | disclosed |
| WO-2020245321-A1 | METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STxB) MONOMERS AND OLIGOMERS, AND USES THEREOF | INSTITUT CURIE (FR) | 2020-12-10 | — | — | WO | disclosed |
| WO-2019243714-A1 | METHOD FOR DETECTING BACTERIA ACCORDING TO THE GRAM SIGNAL THEREOF IN A COMPLEX SAMPLE | MAAT PHARMA (FR) | 2019-12-26 | — | — | WO | disclosed |
| US-9145395-B2 | Inhibition and dispersion of bacterial biofilms with imidazole-triazole derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2015-09-29 | — | — | US | disclosed |
| US-9145395-B2 | Inhibition and dispersion of bacterial biofilms with imidazole-triazole derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2015-09-29 | — | — | US | disclosed |
| US-20130209361-A1 | PROCESS FOR PRODUCING RADIOHALOGENATED BIOCONJUGATES AND PRODUCTS THEREOF | UCL BUSINESS PLC (GB) | 2013-08-15 | — | — | US | disclosed |
| US-20130209361-A1 | PROCESS FOR PRODUCING RADIOHALOGENATED BIOCONJUGATES AND PRODUCTS THEREOF | UCL BUSINESS PLC (GB) | 2013-08-15 | — | — | US | disclosed |
| US-20130129795-A1 | INHIBITION AND DISPERSION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | UNIV NORTH CAROLINA STATE (US) | 2013-05-23 | — | — | US | disclosed |
| WO-2012022932-A1 | PROCESS FOR PRODUCING RADIOHALOGENATED BIOCONJUGATES AND PRODUCTS THEREOF | UCL BUSINESS PLC (GB) | 2012-02-23 | — | — | WO | disclosed |
| US-20110117158-A1 | INHIBITION AND DISPERSION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | MELANDER CHRISTIAN | 2011-05-19 | — | — | US | disclosed |
| US-20110117158-A1 | INHIBITION AND DISPERSION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | MELANDER CHRISTIAN | 2011-05-19 | — | — | US | disclosed |
| US-20110065164-A1 | DOUBLE-LABELLING AGENTS BASED ON VINYL SULPHONE | UNIVERSIDAD DE GRANADA (ES) | 2011-03-17 | — | — | US | disclosed |
| US-7897631-B2 | Inhibition and dispersion of bacterial biofilms with imidazole-triazole derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2011-03-01 | — | — | US | disclosed |
| US-7897631-B2 | Inhibition and dispersion of bacterial biofilms with imidazole-triazole derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2011-03-01 | — | — | US | disclosed |
| WO-2009131654-A2 | INHIBITION AND DISPERSION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-10-29 | — | — | WO | disclosed |
| US-20090263438-A1 | INHIBITION AND DISPERSION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-10-22 | — | — | US | disclosed |
| US-20090263438-A1 | INHIBITION AND DISPERSION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-10-22 | — | — | US | disclosed |
| WO-2009106665-A1 | DOUBLE-LABELLING AGENTS BASED ON VINYL SULPHONE | UNIVERSIDAD DE GRANADA (ES) | 2009-09-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090263438-A1 | INHIBITION AND DISPERSION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | TFPI, O60361, TFPI2 | HDAC4 288/4885HDAC10 595/4885HDAC6 116/4885 |
| US-20110117158-A1 | INHIBITION AND DISPERSION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | TFPI, O60361, TFPI2 | HDAC4 288/4885HDAC10 595/4885HDAC6 116/4885 |
| US-20130209361-A1 | PROCESS FOR PRODUCING RADIOHALOGENATED BIOCONJUGATES AND PRODUCTS THEREOF | QPCT, CBR3, SSTR5 | HDAC4 4381/4885HDAC10 3839/4885HDAC6 2005/4885 |
| US-20130129795-A1 | INHIBITION AND DISPERSION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | TFPI, O60361, TFPI2 | HDAC4 288/4885HDAC10 595/4885HDAC6 116/4885 |
| US-20110065164-A1 | DOUBLE-LABELLING AGENTS BASED ON VINYL SULPHONE | SUMO2, VCL, NEDD4 | HDAC4 3972/4885HDAC10 2489/4885HDAC6 1876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.