SCHEMBL572629

SCHEMBL572629

CN(C)c1cccc2c(S(=O)(=O)NCCO)cccc12

nearest known ligand 0.65

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 1/20 0.65
HDAC10 Q969S8 1/20 0.65
HDAC6 Q9UBN7 1/20 0.65
HDAC5 Q9UQL6 1/20 0.65
EDNRA P25101 3/20 0.63
GBA1 P04062 4/20 0.60
GLB1 P16278 3/20 0.59
F2 P00734 1/20 0.58
PRSS1 P07477 1/20 0.58
PRSS2 P07478 1/20 0.58
PRSS3 P35030 1/20 0.58
EPHX2 P34913 1/20 0.56
KDM4E B2RXH2 1/20 0.55
NSD2 O96028 1/20 0.55
TSHR P16473 1/20 0.55
HSD17B10 Q99714 1/20 0.55
CA2 P00918 1/20 0.55
PTGS2 P35354 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13598031 0.92 HDAC4 (0.60) HDAC4HDAC10HDAC6HDAC5EDNRA
SCHEMBL4782146 0.92 HDAC4 (0.69) HDAC4HDAC10HDAC6HDAC5EDNRA
SCHEMBL4126957 0.88 HDAC4 (0.71) HDAC4HDAC10HDAC6HDAC5EDNRA
SCHEMBL4139459 0.88 HDAC4 (0.75) HDAC4HDAC10HDAC6HDAC5EDNRA
SCHEMBL19922522 0.87 HDAC4 (0.60) HDAC4HDAC10HDAC6HDAC5EDNRA
SCHEMBL12686661 0.87 HDAC4 (0.57) HDAC4HDAC10HDAC6HDAC5EDNRA
SCHEMBL10002025 0.87 HDAC4 (0.62) HDAC4HDAC10HDAC6HDAC5EDNRA
SCHEMBL4142506 0.87 HDAC4 (0.77) HDAC4HDAC10HDAC6HDAC5EDNRA
SCHEMBL19603202 0.86 CYP3A4 (0.57) KDM4ENSD2TSHRHSD17B10
SCHEMBL12502117 0.86 HDAC4 (0.65) HDAC4HDAC10HDAC6HDAC5EDNRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025034780-A1 STATISTICAL CHARGE-ALTERING RELEASABLE TRANSPORTERS FOR NUCLEIC ACID DELIVERY THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2025-02-13 WO claimed
CN-107880988-B Environment-friendly forming oil for stainless steel and preparation method thereof 广州市联诺化工科技有限公司 2021-02-09 CN claimed
US-12622981-B2 Immolative cell-penetrating complexes for nucleic acid delivery THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2026-05-12 US disclosed
US-12527882-B2 Immolative cell-penetrating complexes for nucleic acid delivery THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2026-01-20 US disclosed
EP-4613289-A2 IMMOLATIVE CELL-PENETRATING COMPLEXES FOR NUCLEIC ACID DELIVERY The Board of Trustees of the Leland Stanford Junior University (US) 2025-09-10 EP disclosed
EP-3490562-B1 IMMOLATIVE CELL-PENETRATING COMPLEXES FOR NUCLEIC ACID DELIVERY UNIV LELAND STANFORD JUNIOR (US) 2025-09-03 EP disclosed
WO-2025072271-A1 GUANIDINYLATED SERINOL POLYMERIC NUCLEIC ACID TRANSPORTERS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2025-04-03 WO disclosed
WO-2025034780-A1 STATISTICAL CHARGE-ALTERING RELEASABLE TRANSPORTERS FOR NUCLEIC ACID DELIVERY THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2025-02-13 WO disclosed
US-12215341-B2 Hybrid immolative cell-penetrating complexes for nucleic acid delivery THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2025-02-04 US disclosed
US-20240277870-A1 IMMOLATIVE CELL-PENETRATING COMPLEXES FOR NUCLEIC ACID DELIVERY THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2024-08-22 US disclosed
CN-115252807-A Disaggregated cell-penetrating complexes for nucleic acid delivery 利兰斯坦福初级大学董事会 2022-11-01 CN disclosed
US-7939621-B2 Oligocarbonate molecular transporters INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2011-05-10 US disclosed
US-20110045100-A1 Antimalarial Quinolines and Methods of Use Thereof GEORGETOWN UNIVERSITY (US) 2011-02-24 US disclosed
US-20110045100-A1 Antimalarial Quinolines and Methods of Use Thereof GEORGETOWN UNIVERSITY (US) 2011-02-24 US disclosed
US-20100280219-A1 OLIGOCARBONATE MOLECULAR TRANSPORTERS INTERNATIONAL BUSINESS MACHINES CORPORATION 2010-11-04 US disclosed
US-20100280219-A1 OLIGOCARBONATE MOLECULAR TRANSPORTERS INTERNATIONAL BUSINESS MACHINES CORPORATION 2010-11-04 US disclosed
US-20100280219-A1 OLIGOCARBONATE MOLECULAR TRANSPORTERS INTERNATIONAL BUSINESS MACHINES CORPORATION 2010-11-04 US disclosed
WO-2009148659-A2 ANTIMALARIAL QUINOLINES AND METHODS OF USE THEREOF GEORGETOWN UNIVERSITY (US) 2009-12-10 WO disclosed
WO-2009144344-A2 COMPOUND FOR LABELLING BIOMOLECULES BASED ON VINYLSULPHONE, PREPARATION AND USES UNIVERSIDAD DE GRANADA (ES) 2009-12-03 WO disclosed
US-5512486-A Single step signal group-imidazole labeling of organic phosphate groups under aqueous conditions NORTHEASTERN UNIVERSITY (US) 1996-04-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12622981-B2 Immolative cell-penetrating complexes for nucleic acid delivery NPC1L1, NPC1, SCP2 HDAC4 2147/4885HDAC10 1492/4885HDAC6 2707/4885
US-20240277870-A1 IMMOLATIVE CELL-PENETRATING COMPLEXES FOR NUCLEIC ACID DELIVERY RNASE1, IPO9, DNASE1L3 HDAC4 2992/4885HDAC10 2962/4885HDAC6 2410/4885
US-20110045100-A1 Antimalarial Quinolines and Methods of Use Thereof NQO2, QTRT1, QTRT2 HDAC4 3044/4885HDAC10 2714/4885HDAC6 1030/4885
US-20100280219-A1 OLIGOCARBONATE MOLECULAR TRANSPORTERS SLC10A6, SLCO2B1, SLCO4C1 HDAC4 2793/4885HDAC10 604/4885HDAC6 3336/4885
US-12527882-B2 Immolative cell-penetrating complexes for nucleic acid delivery CCRL2, HAVCR2, CCR3 HDAC4 1782/4885HDAC10 3391/4885HDAC6 2498/4885
US-12215341-B2 Hybrid immolative cell-penetrating complexes for nucleic acid delivery RNASE1, DNASE1L3, IPO9 HDAC4 2538/4885HDAC10 2620/4885HDAC6 2178/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.