Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1031859 | 0.79 | LMNA (0.52) | LMNATRPM8HTR2AHRH1AOC3 | |
| SCHEMBL8576434 | 0.79 | LMNA (0.52) | LMNATRPM8HTR2AHRH1AOC3 | |
| SCHEMBL19370857 | 0.77 | AOC3 (0.43) | LMNATRPM8SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14372108 | 0.75 | AOC3 (0.42) | LMNASLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL11141579 | 0.74 | LMNA (0.47) | LMNATRPM8SLC6A2SLC6A4HTR2A | |
| SCHEMBL1952126 | 0.73 | TRPM8 (0.49) | LMNATRPM8AOC3CYP1A2MEN1 | |
| SCHEMBL12152386 | 0.73 | LMNA (0.37) | LMNATRPM8SLC6A3HTR2AHRH1 | |
| SCHEMBL171013 | 0.73 | HTR2A (0.48) | LMNATRPM8SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8926699 | 0.73 | HTR2A (0.48) | LMNATRPM8SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL119104 | 0.73 | HTR2A (0.48) | LMNATRPM8SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590387-B1 | RING-OPENED AZLACTONE INITIATORS FOR NITROXIDE-MEDIATED POLYMERIZATION | 3M INNOVATIVE PROPERTIES CO (US) | 2009-10-21 | — | — | EP | disclosed |