Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 16/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15410506 | 0.86 | GPR119 (0.52) | GPR119EPHX1HPGD | |
| SCHEMBL16993349 | 0.85 | GPR119 (0.49) | GPR119EPHX1HPGD | |
| SCHEMBL16993387 | 0.84 | HPGD (0.48) | GPR119EPHX1HPGD | |
| SCHEMBL18429024 | 0.79 | GPR119 (0.47) | GPR119EPHX1HPGD | |
| SCHEMBL34473801 | 0.78 | USP30 (0.50) | GPR119EPHX1HPGD | |
| SCHEMBL19918238 | 0.78 | USP30 (0.50) | GPR119EPHX1HPGD | |
| SCHEMBL16082201 | 0.78 | USP30 (0.46) | GPR119HPGD | |
| SCHEMBL7662300 | 0.78 | GPR119 (0.52) | GPR119HPGD | |
| SCHEMBL4426117 | 0.76 | KDM4E (0.55) | GPR119EPHX1HPGD | |
| SCHEMBL13811514 | 0.76 | GPR119 (0.52) | GPR119EPHX1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2108648-A1 | Selected CGRP antagonists, method for their manufacture and use as medicines | Boehringer Ingelheim International GmbH (DE) | 2009-10-14 | — | — | EP | disclosed |