Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT3 | O60678 | 1/20 | 0.32 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.32 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.32 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.32 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27391836 | 0.82 | PRMT3 (0.33) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL9541590 | 0.73 | PRMT3 (0.36) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL25841024 | 0.71 | PRMT3 (0.34) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL8717205 | 0.71 | PRMT1 (0.50) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL18950460 | 0.71 | PRMT1 (0.50) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL29074467 | 0.71 | PRMT1 (0.50) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL29580660 | 0.70 | CA12 (0.40) | SLC2A1 | |
| SCHEMBL29581875 | 0.70 | CA12 (0.40) | SLC2A1 | |
| SCHEMBL254237 | 0.70 | — | — | |
| SCHEMBL26434632 | 0.69 | PRMT3 (0.35) | PRMT3CARM1PRMT6PRMT1PRMT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2108648-A1 | Selected CGRP antagonists, method for their manufacture and use as medicines | Boehringer Ingelheim International GmbH (DE) | 2009-10-14 | — | — | EP | disclosed |