Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT3 | O60678 | 1/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21283080 | 0.86 | EPHX1 (0.37) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL14958730 | 0.86 | EPHX1 (0.37) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL18502845 | 0.86 | EPHX1 (0.37) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL27391836 | 0.81 | PRMT3 (0.33) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL24485297 | 0.78 | CYP2C19 (0.36) | — | |
| SCHEMBL26788415 | 0.76 | CHRNB2 (0.31) | — | |
| SCHEMBL991230 | 0.75 | PRMT3 (0.32) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL13233640 | 0.74 | USP2 (0.33) | — | |
| SCHEMBL19402460 | 0.74 | — | — | |
| SCHEMBL19402489 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3848363-B1 | TRICYCLIC SUBSTITUTED PIPERIDINE DIONE COMPOUND | MEDSHINE DISCOVERY INC (CN) | 2023-07-19 | — | — | EP | disclosed |
| US-5270310-A | N-aminoalkyl amide inhibitors of protein kinase C | SPHINX PHARMACEUTICALS CORPORATION (US) | 1993-12-14 | — | — | US | disclosed |
| WO-1993011758-A1 | N-AMINOALKYL AMIDE INHIBITORS OF PROTEIN KINASE C | SPHINX PHARMACEUTICALS CORPORATION (US) | 1993-06-24 | — | — | WO | disclosed |