Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13950295 | 0.91 | PAOX (0.39) | TSHRHTTLMNAMAPK1CYP3A4 | |
| SCHEMBL14397158 | 0.91 | PAOX (0.39) | TSHRHTTLMNAMAPK1CYP3A4 | |
| SCHEMBL2105851 | 0.88 | TSHR (0.57) | TSHRHTTLMNAMAPK1CYP3A4 | |
| SCHEMBL18638052 | 0.88 | TSHR (0.57) | TSHRHTTLMNAMAPK1CYP3A4 | |
| SCHEMBL8436259 | 0.86 | MAPK1 (0.40) | TSHRHTTLMNAMAPK1ALDH1A1 | |
| SCHEMBL9884583 | 0.86 | MAPK1 (0.40) | TSHRHTTLMNAMAPK1ALDH1A1 | |
| SCHEMBL13810733 | 0.85 | ALDH1A1 (0.35) | TSHRLMNAMAPK1CYP3A4ALDH1A1 | |
| SCHEMBL17485794 | 0.84 | TSHR (0.48) | TSHRHTTLMNAMAPK1CYP3A4 | |
| SCHEMBL15492738 | 0.83 | PAOX (0.34) | TSHRHTTLMNAMAPK1CYP3A4 | |
| SCHEMBL11086397 | 0.83 | CYP2D6 (0.48) | TSHRHTTLMNAMAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247738-A1 | BIOCOMPATIBLE POLY-BETA-1-4-N-ACETYLGLUCOSAMINE | MARINE POLYMER TECHNOLOGIES, INC. | 2009-10-01 | — | — | US | disclosed |