Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 11/20 | 0.50 |
| ▸ | PPARG | P37231 | 8/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13655823 | 1.00 | PPARA (0.50) | PPARAPPARGSIGMAR1MAPTACACB | |
| SCHEMBL13656061 | 0.88 | SIGMAR1 (0.43) | PPARAPPARGSIGMAR1MAPTGRIN1 | |
| SCHEMBL13655975 | 0.88 | PPARG (0.44) | PPARAPPARGSIGMAR1POLB | |
| SCHEMBL4075627 | 0.87 | PPARA (0.69) | PPARAPPARG | |
| SCHEMBL4080000 | 0.87 | PPARA (0.69) | PPARAPPARG | |
| SCHEMBL13655817 | 0.86 | PPARG (0.48) | PPARAPPARGMAPTACACB | |
| SCHEMBL4073415 | 0.84 | PPARA (0.56) | PPARAPPARG | |
| SCHEMBL4076344 | 0.84 | PPARA (0.56) | PPARAPPARG | |
| SCHEMBL4797636 | 0.81 | FFAR1 (0.52) | PPARAPPARG | |
| SCHEMBL13655889 | 0.81 | PPARG (0.53) | PPARAPPARGMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7598293-B2 | Compounds and their use in medicine, process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S LABORATORIES, INC. (US) | 2009-10-06 | — | — | US | disclosed |