SCHEMBL136559

SCHEMBL136559

NNc1ccc2c(S(=O)(=O)O)cc(S(=O)(=O)O)cc2c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 1/20 0.50
NT5E P21589 2/20 0.47
CASP6 P55212 5/20 0.46
NSD2 O96028 3/20 0.46
DUSP3 P51452 2/20 0.46
PTPN5 P54829 2/20 0.46
PTPN11 Q06124 2/20 0.46
ALDH1A1 P00352 2/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
HSD17B10 Q99714 1/20 0.45
CTDSP1 Q9GZU7 1/20 0.45
ENPP2 Q13822 2/20 0.44
CASP7 P55210 1/20 0.43
SNCA P37840 2/20 0.40
CD40 P25942 1/20 0.39
CD40LG P29965 1/20 0.39
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30863681 1.00 PRMT1 (0.50) PRMT1NT5ECASP6NSD2DUSP3
SCHEMBL28395631 0.98 PRMT1 (0.49) PRMT1NT5ECASP6NSD2DUSP3
Hydrochloric Acid SCHEMBL1715106 0.98 PRMT1 (0.49) PRMT1NT5ECASP6NSD2DUSP3
Hydrochloric Acid SCHEMBL1715110 0.98 PRMT1 (0.49) PRMT1NT5ECASP6NSD2DUSP3
SCHEMBL11154841 0.84 PRMT1 (0.50) PRMT1NT5ECASP6NSD2DUSP3
SCHEMBL12620598 0.84 PRMT1 (0.70) PRMT1NT5ECASP6NSD2DUSP3
Naphthalene Trisulfonate SCHEMBL306176 0.83 CASP6 (0.58) PRMT1NT5ECASP6NSD2DUSP3
Naphthalene Trisulfonate SCHEMBL29431498 0.83 CASP6 (0.58) PRMT1NT5ECASP6NSD2DUSP3
Naphthalene Trisulfonate SCHEMBL305166 0.83 CASP6 (0.58) PRMT1NT5ECASP6NSD2DUSP3
SCHEMBL14299276 0.83 PRMT1 (0.49) PRMT1NT5ECASP6NSD2DUSP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4491743-A2 NOVEL QUENCHER AND REPORTER DYE COMBINATIONS Life Technologies Corporation (US) 2025-01-15 EP disclosed
WO-2024143263-A1 FLUORESCENCE INTENSITY ENHANCING AGENT, METHOD FOR ENHANCING FLUORESCENCE INTENSITY OF FLUORESCENTLY LABELED TARGET BIOLOGICAL MATERIAL, AND FLUORESCENCE DETECTION KIT 富士フイルム株式会社 2024-07-04 WO disclosed
CN-117529529-A Azaindole cyanine dye, application and preparation method 生命技术公司 2024-02-06 CN disclosed
US-20230159547-A1 COMPOUND AND LABELED BIOLOGICAL SUBSTANCE USING THE SAME FUJIFILM CORPORATION (JP) 2023-05-25 US disclosed
US-20230159547-A1 COMPOUND AND LABELED BIOLOGICAL SUBSTANCE USING THE SAME FUJIFILM CORPORATION (JP) 2023-05-25 US disclosed
US-20230124451-A1 NOVEL QUENCHER AND REPORTER DYE COMBINATIONS Life Technologies Corporation 2023-04-20 US disclosed
WO-2023004356-A2 AZAINDOLE CYANINE DYES, USES, AND METHODS OF PREPARATION Life Technologies Corporation (US) 2023-01-26 WO disclosed
US-11535885-B2 Quencher and reporter dye combinations Life Technologies Corporation 2022-12-27 US disclosed
US-11535885-B2 Quencher and reporter dye combinations Life Technologies Corporation 2022-12-27 US disclosed
WO-2021215514-A1 COMPOUND AND LABELED BIOMATERIAL IN WHICH SAME IS USED 富士フイルム株式会社 (JP) 2021-10-28 WO disclosed
US-6977305-B2 Modified carbocyanine dyes and their conjugates MOLECULAR PROBES, INC. (US) 2005-12-20 US disclosed
US-6974873-B2 Modified carbocyanine dyes and their conjugates MOLECULAR PROBES, INC. (US) 2005-12-13 US disclosed
EP-1394219-A1 PH sensitive cyanine dyes as reactive fluorescent reagents CARNEGIE-MELLON UNIVERSITY (US) 2004-03-03 EP disclosed
EP-1322710-A1 MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES Molecular Probes Inc. (US) 2003-07-02 EP disclosed
US-20020077487-A1 Modified carbocyanine dyes and their conjugates MOLECULAR PROBES, INC. 2002-06-20 US disclosed
EP-1212375-A2 PH SENSITIVE CYANINE DYES AS REACTIVE FLUORESCENT REAGENTS CARNEGIE-MELLON UNIVERSITY (US) 2002-06-12 EP disclosed
US-20020064794-A1 Modified carbocyanine dyes and their conjugates MOLECULAR PROBES, INC. 2002-05-30 US disclosed
WO-2000075237-A9 pH SENSITIVE CYANINE DYES AS REACTIVE FLUORESCENT REAGENTS UNIV CARNEGIE MELLON (US) 2002-05-10 WO disclosed
WO-2002026891-A1 MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES MOLECULAR PROBES, INC. (US) 2002-04-04 WO disclosed
WO-2000075237-A2 pH SENSITIVE CYANINE DYES AS REACTIVE FLUORESCENT REAGENTS CARNEGIE MELLON UNIVERSITY (US) 2000-12-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230159547-A1 COMPOUND AND LABELED BIOLOGICAL SUBSTANCE USING THE SAME CD209, MRPL9, RXFP1 PRMT1 18/4885NT5E 2942/4885CASP6 1358/4885
US-20020077487-A1 Modified carbocyanine dyes and their conjugates IK, CBR3, DRD5 PRMT1 2240/4885NT5E 717/4885CASP6 3112/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.