SCHEMBL11154841

SCHEMBL11154841

CNc1ccc2c(S(=O)(=O)O)cc(S(=O)(=O)O)cc2c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 1/20 0.50
CASP6 P55212 5/20 0.47
NSD2 O96028 3/20 0.47
NT5E P21589 2/20 0.47
DUSP3 P51452 2/20 0.47
PTPN5 P54829 2/20 0.47
PTPN11 Q06124 2/20 0.47
CASP7 P55210 1/20 0.47
ENPP2 Q13822 4/20 0.44
CTDSP1 Q9GZU7 1/20 0.42
SNCA P37840 2/20 0.42
ALDH1A1 P00352 3/20 0.41
HSD17B10 Q99714 2/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
HIF1A Q16665 2/20 0.41
TP53 P04637 1/20 0.41
CYP3A4 P08684 1/20 0.41
THRB P10828 1/20 0.41
HPGD P15428 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11149987 0.98 PRMT1 (0.49) PRMT1CASP6NSD2NT5EDUSP3
SCHEMBL13818469 0.90 CASP6 (0.54) PRMT1CASP6NSD2NT5EDUSP3
SCHEMBL7537842 0.86 ENPP2 (0.49) PRMT1CASP6NSD2NT5EDUSP3
SCHEMBL7537836 0.85 ENPP2 (0.48) PRMT1CASP6NSD2NT5EDUSP3
SCHEMBL13705658 0.84 CA12 (0.49) PRMT1CASP6NSD2NT5EDUSP3
SCHEMBL136559 0.84 PRMT1 (0.50) PRMT1CASP6NSD2NT5EDUSP3
SCHEMBL30863681 0.84 PRMT1 (0.50) PRMT1CASP6NSD2NT5EDUSP3
SCHEMBL1374756 0.84 PRMT1 (0.70) PRMT1CASP6NSD2NT5EDUSP3
SCHEMBL37480409 0.84 PRMT1 (0.70) PRMT1CASP6NSD2NT5EDUSP3
Naphthalene Trisulfonate SCHEMBL306176 0.83 CASP6 (0.58) PRMT1CASP6NSD2NT5EDUSP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4376737-A Process for the production of naphthylaminehydroxysulphonic acids CIBA-GEIGY AG (CH) 1983-03-15 US claimed
US-7875412-B2 silanetriol sulfonate complexes; for printers, copiers, facsimile machines; improved durability and environmental resistance ORIENT CHEMICAL INDUSTRIES, LTD. (JP) 2011-01-25 US disclosed
US-20070231726-A1 Positive electrified charge control agent and positive electrified toner for developing electrostatic image ORIENT CHEMICAL INDUSTRIES, LTD. (JP) 2007-10-04 US disclosed
US-4376737-A Process for the production of naphthylaminehydroxysulphonic acids CIBA-GEIGY AG (CH) 1983-03-15 US disclosed