SCHEMBL1365591

SCHEMBL1365591

O=C(CCCCCCCBr)OCc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.58
MAPK1 P28482 2/20 0.58
L3MBTL1 Q9Y468 2/20 0.58
TDP1 Q9NUW8 2/20 0.53
KMT2A Q03164 2/20 0.53
SLC6A2 P23975 1/20 0.53
SLC6A3 Q01959 1/20 0.53
EPHX2 P34913 1/20 0.51
LMNA P02545 2/20 0.49
HTT P42858 1/20 0.46
FAAH O00519 1/20 0.45
MGLL Q99685 1/20 0.45
HCAR2 Q8TDS4 1/20 0.45
NOTUM Q6P988 1/20 0.45
MAPT P10636 2/20 0.44
MEN1 O00255 1/20 0.44
POLB P06746 1/20 0.44
RXFP1 Q9HBX9 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2C9 P11712 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1365835 1.00 ALDH1A1 (0.58) ALDH1A1MAPK1L3MBTL1TDP1KMT2A
SCHEMBL18762322 1.00 ALDH1A1 (0.58) ALDH1A1MAPK1L3MBTL1TDP1KMT2A
SCHEMBL3871093 1.00 ALDH1A1 (0.58) ALDH1A1MAPK1L3MBTL1TDP1KMT2A
SCHEMBL24677830 1.00 ALDH1A1 (0.58) ALDH1A1MAPK1L3MBTL1TDP1KMT2A
SCHEMBL1419528 1.00 ALDH1A1 (0.58) ALDH1A1MAPK1L3MBTL1TDP1KMT2A
SCHEMBL24678064 1.00 ALDH1A1 (0.58) ALDH1A1MAPK1L3MBTL1TDP1KMT2A
SCHEMBL7545592 1.00 ALDH1A1 (0.58) ALDH1A1MAPK1L3MBTL1TDP1KMT2A
SCHEMBL5386843 1.00 ALDH1A1 (0.58) ALDH1A1MAPK1L3MBTL1TDP1KMT2A
SCHEMBL318699 1.00 ALDH1A1 (0.58) ALDH1A1MAPK1L3MBTL1TDP1KMT2A
SCHEMBL1363586 0.98 ALDH1A1 (0.59) ALDH1A1MAPK1L3MBTL1TDP1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117903225-A Liver tissue targeted delivery compound, preparation method and application thereof 思合基因(北京)生物科技有限公司 2024-04-19 CN disclosed
US-11833208-B2 PLK1 selective degradation inducing compound UPPTHERA, INC. (KR) 2023-12-05 US disclosed
US-11833208-B2 PLK1 selective degradation inducing compound UPPTHERA, INC. (KR) 2023-12-05 US disclosed
US-20230372498-A1 PLK1 SELECTIVE DEGRADATION INDUCING COMPOUND UPPTHERA (KR) 2023-11-23 US disclosed
US-20230372498-A1 PLK1 SELECTIVE DEGRADATION INDUCING COMPOUND UPPTHERA (KR) 2023-11-23 US disclosed
EP-3476832-B1 CATIONIC LIPID EISAI R&D MAN CO LTD (JP) 2023-04-19 EP disclosed
EP-3733647-B1 CATIONIC LIPID EISAI R&D MAN CO LTD (JP) 2022-06-15 EP disclosed
EP-3733647-B1 CATIONIC LIPID EISAI R&D MAN CO LTD (JP) 2022-06-15 EP disclosed
CN-109311809-B Cationic lipids 卫材R&D管理有限公司 2022-04-08 CN disclosed
EP-2880012-B1 COMPOUNDS PHOTOCURE ASA (NO) 2021-12-15 EP disclosed
WO-2005121904-A1 CHARGE CONTROL AGENT, TONER, IMAGE FORMING METHOD, AND IMAGE FORMING APPARATUS CANON KABUSHIKI KAISHA (JP) 2005-12-22 WO disclosed
EP-1105399-B1 CARBOXYLATED PHOSPHATIDIC ACID ESTERS BRACCO RESEARCH SA (CH) 2004-04-14 EP disclosed
US-6706280-B2 DRUG TARGETING WITH LIPOSOMES AND MAGNETIC RESONANCE IMAGING CONTRAST MEDIA FOR DIAGNOSTICS BRACCO RESEARCH S.A. (CH) 2004-03-16 US disclosed
US-20020136760-A1 CARBOXYLATED PHOSPHATIDIC ACID ESTERS BRACCO RESEARCH S.A. (CH) 2002-09-26 US disclosed
EP-1105399-A1 CARBOXYLATED PHOSPHATIDIC ACID ESTERS BRACCO RESEARCH S.A. (CH) 2001-06-13 EP disclosed
WO-2000011007-A1 CARBOXYLATED PHOSPHATIDIC ACID ESTERS BRACCO RESEARCH S.A. (CH) 2000-03-02 WO disclosed
US-5846954-A Cyclodextrin compounds and methods of making and use thereof THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 1998-12-08 US disclosed
US-5760015-A FOR MODULATING CELLULAR GROWTH ACTIVITY THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 1998-06-02 US disclosed
EP-0824352-A1 CYCLODEXTRIN COMPOUNDS AND METHODS OF MAKING AND USE THEREOF THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 1998-02-25 EP disclosed
WO-1996031220-A1 CYCLODEXTRIN COMPOUNDS AND METHODS OF MAKING AND USE THEREOF THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 1996-10-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230372498-A1 PLK1 SELECTIVE DEGRADATION INDUCING COMPOUND PLK1, BUB1B, BUB1 ALDH1A1 3592/4885MAPK1 1316/4885L3MBTL1 719/4885
US-20020136760-A1 CARBOXYLATED PHOSPHATIDIC ACID ESTERS PHOSPHO1, PLD1, SGMS1 ALDH1A1 1522/4885MAPK1 2643/4885L3MBTL1 1472/4885
US-11833208-B2 PLK1 selective degradation inducing compound PLK1, BUB1B, BUB1 ALDH1A1 3592/4885MAPK1 1316/4885L3MBTL1 719/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.