Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B7 | P56937 | 1/20 | 0.60 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.59 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7529348 | 1.00 | HSD17B7 (0.60) | HSD17B7SRD5A1SRD5A2 | |
| SCHEMBL7527383 | 1.00 | HSD17B7 (0.60) | HSD17B7SRD5A1SRD5A2 | |
| SCHEMBL7527375 | 1.00 | HSD17B7 (0.60) | HSD17B7SRD5A1SRD5A2 | |
| SCHEMBL14561091 | 0.84 | SRD5A1 (0.56) | HSD17B7SRD5A1SRD5A2 | |
| SCHEMBL7524799 | 0.84 | HSD17B7 (0.57) | HSD17B7SRD5A1SRD5A2 | |
| SCHEMBL5408042 | 0.84 | SRD5A1 (0.56) | HSD17B7SRD5A1SRD5A2 | |
| SCHEMBL5427981 | 0.84 | SRD5A1 (0.56) | SRD5A1SRD5A2 | |
| SCHEMBL7524800 | 0.84 | HSD17B7 (0.57) | HSD17B7SRD5A1SRD5A2 | |
| SCHEMBL5408037 | 0.84 | SRD5A1 (0.56) | HSD17B7SRD5A1SRD5A2 | |
| SCHEMBL10273977 | 0.84 | CYP19A1 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7605152-B2 | 17-hydroxy-4-aza-androstan-3-ones as androgen receptor modulators | MERCK & CO., INC. (US) | 2009-10-20 | — | — | US | disclosed |
| US-7605152-B2 | 17-hydroxy-4-aza-androstan-3-ones as androgen receptor modulators | MERCK & CO., INC. (US) | 2009-10-20 | — | — | US | disclosed |