Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDAH1 | O94760 | 1/20 | 0.34 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.34 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.34 |
| ▸ | ENGASE | Q8NFI3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tenatoprazole SCHEMBL13657657 | 0.97 | DDAH1 (0.31) | DDAH1SARM1IDO2ENGASE | |
| Tenatoprazole SCHEMBL13657651 | 0.96 | DDAH1 (0.34) | DDAH1SARM1IDO2ENGASE | |
| Tenatoprazole SCHEMBL13657649 | 0.95 | DDAH1 (0.37) | DDAH1SARM1IDO2ENGASE | |
| Tenatoprazole SCHEMBL13657655 | 0.94 | — | — | |
| Tenatoprazole SCHEMBL13657687 | 0.92 | DDAH1 (0.32) | DDAH1SARM1IDO2ENGASE | |
| Tenatoprazole SCHEMBL13657633 | 0.91 | DDAH1 (0.34) | DDAH1SARM1IDO2ENGASE | |
| Tenatoprazole SCHEMBL13657656 | 0.91 | — | — | |
| Tenatoprazole SCHEMBL13657644 | 0.91 | DDAH1 (0.43) | DDAH1SARM1IDO2ENGASE | |
| Tenatoprazole SCHEMBL13657653 | 0.90 | — | — | |
| Tenatoprazole SCHEMBL13657648 | 0.90 | DDAH1 (0.32) | DDAH1SARM1IDO2ENGASE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090258897-A1 | Substituted benzimidazoles | AUSPEX PHARMACEUTICALS, INC. (US) | 2009-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258897-A1 | Substituted benzimidazoles | ABCB11, CYP2C19, HRH2 | DDAH1 3318/4885SARM1 1497/4885IDO2 3233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.