Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL731324 | 1.00 | TRPA1 (0.56) | TRPA1ALDH1A1TSHRMAPK1TDP1 | |
| SCHEMBL731323 | 1.00 | TRPA1 (0.56) | TRPA1ALDH1A1TSHRMAPK1TDP1 | |
| SCHEMBL21831066 | 1.00 | TRPA1 (0.56) | TRPA1ALDH1A1TSHRMAPK1TDP1 | |
| SCHEMBL93753 | 0.95 | — | — | |
| SCHEMBL6481571 | 0.95 | — | — | |
| SCHEMBL3627580 | 0.95 | — | — | |
| SCHEMBL6481787 | 0.95 | — | — | |
| SCHEMBL93751 | 0.95 | — | — | |
| SCHEMBL4273061 | 0.89 | TRPA1 (0.47) | TRPA1ALDH1A1PPARA | |
| SCHEMBL4273062 | 0.89 | TRPA1 (0.47) | TRPA1ALDH1A1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7605182-B2 | drug conjugate with a marker for imaging to detect by fluorescence, X-ray, computerized tomography, magnetic resonance imaging (MRI), radio-isotope scan, single photon emission tomography (SPECT) or positron emission tomography (PET scan); targeting anticancer drugs to the tumor in body | APOSENSE LTD. (IL) | 2009-10-20 | — | — | US | disclosed |