SCHEMBL731323

SCHEMBL731323

CC/C=C/C=C/C=C/CC

nearest known ligand 0.56

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.56
ALDH1A1 P00352 2/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
PPARA Q07869 1/20 0.32
FPR2 P25090 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13660441 1.00 TRPA1 (0.56) TRPA1ALDH1A1TSHRMAPK1TDP1
SCHEMBL731324 1.00 TRPA1 (0.56) TRPA1ALDH1A1TSHRMAPK1TDP1
SCHEMBL21831066 1.00 TRPA1 (0.56) TRPA1ALDH1A1TSHRMAPK1TDP1
SCHEMBL93753 0.95
SCHEMBL6481571 0.95
SCHEMBL3627580 0.95
SCHEMBL6481787 0.95
SCHEMBL93751 0.95
SCHEMBL4273061 0.89 TRPA1 (0.47) TRPA1ALDH1A1PPARA
SCHEMBL4273062 0.89 TRPA1 (0.47) TRPA1ALDH1A1PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6720468-B2 BY REACTING WITH A DIELS-ALDER DIENOPHILE TO PROVIDE A FLUID COMPRISING A DIELS-ALDER ADDUCT AND MONOOLEFINS; AND RECOVERING A RESULTING MONOOLEFIN-CONTAINING FLUID CHEVRON PHILLIPS CHEMICAL COMPANY LP 2004-04-13 US claimed
US-20020165420-A1 Process for the removal of conjugated olefins from a monoolefin stream CHEVRON PHILLIPS CHEMICAL COMPANY LP 2002-11-07 US claimed
US-8889802-B2 Polymer compositions and methods of making and using same POLYMERIGHT, INC. (US) 2014-11-18 US disclosed
US-20120130040-A1 Polymer Compositions and Methods of Making and Using Same POLYMERIGHT, INC. (US) 2012-05-24 US disclosed
EP-2448990-A1 POLYMER COMPOSITIONS AND METHODS OF MAKING AND USING SAME Polymeright Inc. (US) 2012-05-09 EP disclosed
US-8138278-B2 Polymer compositions and methods of making and using same POLYMERIGHT, INC. (US) 2012-03-20 US disclosed
US-20110152492-A1 Polymer Compositions and Methods of Making and Using Same POLYMERIGHT, INC. (US) 2011-06-23 US disclosed
WO-2011008480-A1 POLYMER COMPOSITIONS AND METHODS OF MAKING AND USING SAME POLYMERIGHT, INC. (US) 2011-01-20 WO disclosed
US-7411108-B2 Process for the removal of conjugated olefins from a monoolefin stream CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2008-08-12 US disclosed
US-20040260137-A1 Process for the removal of conjugated olefins from a monoolefin stream CHEVRON PHILLIPS CHEMICAL COMPANY LP 2004-12-23 US disclosed
US-6720468-B2 BY REACTING WITH A DIELS-ALDER DIENOPHILE TO PROVIDE A FLUID COMPRISING A DIELS-ALDER ADDUCT AND MONOOLEFINS; AND RECOVERING A RESULTING MONOOLEFIN-CONTAINING FLUID CHEVRON PHILLIPS CHEMICAL COMPANY LP 2004-04-13 US disclosed
US-20020165420-A1 Process for the removal of conjugated olefins from a monoolefin stream CHEVRON PHILLIPS CHEMICAL COMPANY LP 2002-11-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040260137-A1 Process for the removal of conjugated olefins from a monoolefin stream AKR7A2, DERA, APEX1 TRPA1 2996/4885ALDH1A1 142/4885TSHR 4770/4885
US-20020165420-A1 Process for the removal of conjugated olefins from a monoolefin stream ADH1C, ADH1A, OXER1 TRPA1 4450/4885ALDH1A1 58/4885TSHR 4613/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.