Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4295594 | 1.00 | ALDH1A1 (0.55) | ALDH1A1TSHRKDM4EHSD17B10 | |
| SCHEMBL10770146 | 0.95 | ALDH1A1 (0.50) | ALDH1A1TSHRKDM4EHSD17B10 | |
| SCHEMBL28534124 | 0.95 | ALDH1A1 (0.53) | ALDH1A1TSHRKDM4EHSD17B10 | |
| SCHEMBL4295389 | 0.89 | HRH3 (0.55) | ALDH1A1TSHRKDM4EHSD17B10 | |
| SCHEMBL4295384 | 0.89 | HRH3 (0.55) | ALDH1A1TSHRKDM4EHSD17B10 | |
| SCHEMBL4295391 | 0.89 | HRH3 (0.55) | ALDH1A1TSHRKDM4EHSD17B10 | |
| SCHEMBL4295387 | 0.89 | HRH3 (0.55) | ALDH1A1TSHRKDM4EHSD17B10 | |
| SCHEMBL13660536 | 0.89 | HRH3 (0.55) | ALDH1A1TSHRKDM4EHSD17B10 | |
| SCHEMBL13660580 | 0.84 | ALDH1A1 (0.55) | ALDH1A1TSHRKDM4EHSD17B10 | |
| SCHEMBL4296694 | 0.78 | TSHR (0.46) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090263322-A1 | OCTAHYDRO-INDOLIZINE AND QUINOLIZINE AND HEXAHYDRO-PYRROLIZINES | APODACA RICHARD | 2009-10-22 | — | — | US | disclosed |
| US-20090263322-A1 | OCTAHYDRO-INDOLIZINE AND QUINOLIZINE AND HEXAHYDRO-PYRROLIZINES | APODACA RICHARD | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090263322-A1 | OCTAHYDRO-INDOLIZINE AND QUINOLIZINE AND HEXAHYDRO-PYRROLIZINES | HRH4, HNMT, HRH1 | ALDH1A1 2994/4885TSHR 2532/4885KDM4E 2041/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.