Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.43 |
| ▸ | LTA4H | P09960 | 12/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4288775 | 0.93 | LTA4H (0.41) | HRH3LTA4HKCNH2CHEK2 | |
| SCHEMBL13660544 | 0.80 | HRH3 (0.56) | HRH3LTA4HKCNH2CYP3A4CYP2C9 | |
| SCHEMBL4293402 | 0.80 | HRH3 (0.56) | HRH3LTA4HKCNH2CYP3A4CYP2C9 | |
| SCHEMBL4293480 | 0.79 | HRH3 (0.49) | HRH3LTA4HKCNH2CYP3A4CYP2C9 | |
| SCHEMBL4293467 | 0.79 | HRH3 (0.49) | HRH3LTA4HKCNH2CYP3A4CYP2C9 | |
| SCHEMBL4293472 | 0.79 | HRH3 (0.49) | HRH3LTA4HKCNH2CYP3A4CYP2C9 | |
| SCHEMBL4431777 | 0.79 | HRH3 (0.66) | HRH3KCNH2CYP3A4CYP2C9 | |
| SCHEMBL4438040 | 0.79 | HRH3 (0.66) | HRH3KCNH2CYP3A4CYP2C9 | |
| SCHEMBL6701198 | 0.79 | HRH3 (0.66) | HRH3KCNH2CYP3A4CYP2C9 | |
| SCHEMBL4294139 | 0.79 | HRH3 (0.66) | HRH3KCNH2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090263322-A1 | OCTAHYDRO-INDOLIZINE AND QUINOLIZINE AND HEXAHYDRO-PYRROLIZINES | APODACA RICHARD | 2009-10-22 | — | — | US | disclosed |
| US-20090263322-A1 | OCTAHYDRO-INDOLIZINE AND QUINOLIZINE AND HEXAHYDRO-PYRROLIZINES | APODACA RICHARD | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090263322-A1 | OCTAHYDRO-INDOLIZINE AND QUINOLIZINE AND HEXAHYDRO-PYRROLIZINES | HRH4, HNMT, HRH1 | HRH3 7/4885LTA4H 399/4885KCNH2 470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.