Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.54 |
| ▸ | PREP | P48147 | 3/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | MET | P08581 | 1/20 | 0.51 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31258485 | 0.88 | MEN1 (0.55) | HRH3PREPOPRK1 | |
| SCHEMBL7561453 | 0.85 | SPHK2 (0.53) | PREPACE2 | |
| SCHEMBL5267939 | 0.84 | SPHK2 (0.58) | PREPACE2 | |
| SCHEMBL4602602 | 0.84 | SPHK2 (0.58) | PREPACE2 | |
| SCHEMBL809494 | 0.84 | SPHK2 (0.58) | PREPACE2 | |
| SCHEMBL9202571 | 0.83 | ACE2 (0.56) | PREPACE2 | |
| SCHEMBL809403 | 0.83 | ACE2 (0.56) | PREPACE2 | |
| SCHEMBL7318776 | 0.83 | PREP (0.55) | PREPACE2 | |
| SCHEMBL1122261 | 0.83 | PREP (0.55) | PREPACE2 | |
| SCHEMBL10903579 | 0.83 | CTRB1 (0.57) | PREPACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009131246-A1 | SORDARIN DERIVATIVES FOR PREVENTING OR TREATING INFECTIOUS DISEASES CAUSED BY PATHOGENIC MICROORGANISMS | ASTELLAS PHARMA INC. (JP) | 2009-10-29 | — | — | WO | disclosed |