Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.51 |
| ▸ | PREP | P48147 | 2/20 | 0.51 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13660819 | 0.88 | HRH3 (0.61) | HRH3PREPOPRK1 | |
| SCHEMBL1190565 | 0.82 | SPHK2 (0.54) | PREPTMEM97SIGMAR1FKBP1A | |
| SCHEMBL80752 | 0.82 | SPHK2 (0.54) | PREPTMEM97SIGMAR1FKBP1A | |
| SCHEMBL3605585 | 0.82 | SPHK2 (0.54) | PREPTMEM97SIGMAR1FKBP1A | |
| SCHEMBL2961611 | 0.81 | TMEM97 (0.50) | HRH3TMEM97SIGMAR1OPRK1FKBP1A | |
| SCHEMBL13961188 | 0.81 | SMN1; SMN2 (0.52) | PREPTMEM97SIGMAR1FKBP1A | |
| SCHEMBL13198885 | 0.81 | NPC1 (0.60) | MEN1KMT2APREPTMEM97SIGMAR1 | |
| SCHEMBL5305188 | 0.81 | SMN1; SMN2 (0.52) | PREPTMEM97SIGMAR1FKBP1A | |
| SCHEMBL14646609 | 0.81 | NPC1 (0.60) | MEN1KMT2APREPTMEM97SIGMAR1 | |
| SCHEMBL1778110 | 0.81 | SMN1; SMN2 (0.51) | KMT2APREPTMEM97SIGMAR1FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115715289-B | Polyarylate and application thereof | 江苏先声药业有限公司 | 2024-12-03 | — | — | CN | disclosed |