Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | GSK3B | P49841 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2968523 | 0.89 | GSK3B (0.57) | MMP1MEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL28750349 | 0.85 | MMP1 (0.65) | MMP1MEN1KMT2AGAATDP1 | |
| SCHEMBL10865120 | 0.85 | MMP1 (0.69) | MMP1MEN1KMT2AGAATDP1 | |
| SCHEMBL11149859 | 0.83 | MMP1 (0.67) | MMP1MEN1KMT2AGAATDP1 | |
| SCHEMBL28750318 | 0.82 | MMP1 (0.61) | MMP1MEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL6142809 | 0.81 | MMP1 (0.59) | MMP1MEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL28750319 | 0.81 | MMP1 (0.60) | MMP1MEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL6609685 | 0.80 | MMP1 (0.63) | MMP1MEN1KMT2AGAATDP1 | |
| SCHEMBL16552727 | 0.80 | GSK3B (0.70) | MMP1MEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL11686001 | 0.80 | SMN1; SMN2 (0.62) | MMP1KMT2AGAATDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009126782-A1 | HISTAMINE H3 RECEPTOR LIGANDS | HIGH POINT PHARMACEUTICALS, LLC (US) | 2009-10-15 | — | — | WO | disclosed |