Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 3/20 | 0.63 |
| ▸ | GSK3B | P49841 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6610011 | 0.95 | MMP1 (0.61) | MMP1GSK3BNPC1L3MBTL1MEN1 | |
| SCHEMBL11149859 | 0.90 | MMP1 (0.67) | MMP1GSK3BNPC1L3MBTL1MEN1 | |
| SCHEMBL2235019 | 0.89 | GSK3B (0.63) | MMP1GSK3BNPC1L3MBTL1MEN1 | |
| SCHEMBL5661734 | 0.87 | MMP1 (0.60) | MMP1NPC1L3MBTL1MEN1KMT2A | |
| SCHEMBL28750318 | 0.85 | MMP1 (0.61) | MMP1NPC1L3MBTL1MEN1KMT2A | |
| SCHEMBL27570052 | 0.84 | GSK3B (0.57) | GSK3BNPC1L3MBTL1MEN1KMT2A | |
| SCHEMBL5660844 | 0.84 | GSK3B (0.61) | MMP1GSK3BNPC1L3MBTL1MEN1 | |
| SCHEMBL28750319 | 0.84 | MMP1 (0.60) | MMP1NPC1L3MBTL1MEN1KMT2A | |
| SCHEMBL5660040 | 0.82 | GSK3B (0.59) | GSK3BNPC1L3MBTL1MEN1KMT2A | |
| SCHEMBL5662338 | 0.82 | GSK3B (0.59) | GSK3BNPC1L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140895-B1 | THIOPYRAN COMPOUNDS AS INHIBITORS OF MMP | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-03-24 | — | — | EP | disclosed |