Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PTP4A1 | Q93096 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13237294 | 0.81 | ALDH1A1 (0.53) | ALDH1A1TSHRCYP2C9MAPTKMT2A | |
| SCHEMBL14019201 | 0.81 | ALDH1A1 (0.53) | ALDH1A1TSHRCYP2C9MAPTKMT2A | |
| SCHEMBL16043759 | 0.81 | ALDH1A1 (0.53) | ALDH1A1TSHRCYP2C9MAPTKMT2A | |
| SCHEMBL15055595 | 0.81 | ALDH1A1 (0.53) | ALDH1A1TSHRCYP2C9MAPTKMT2A | |
| SCHEMBL14776464 | 0.80 | ALDH1A1 (0.57) | ALDH1A1TSHRCYP2C9MAPTKMT2A | |
| SCHEMBL24014841 | 0.79 | ALDH1A1 (0.52) | ALDH1A1TSHRCYP2C9MAPTKMT2A | |
| SCHEMBL16534922 | 0.79 | ALDH1A1 (0.52) | ALDH1A1TSHRCYP2C9MAPTKMT2A | |
| SCHEMBL9978312 | 0.78 | ALDH1A1 (0.55) | ALDH1A1TSHRCYP2C9MAPTKMT2A | |
| SCHEMBL5496037 | 0.78 | ALDH1A1 (0.53) | ALDH1A1TSHRMAPTKMT2AMEN1 | |
| SCHEMBL14809891 | 0.78 | ALDH1A1 (0.50) | ALDH1A1TSHRCYP2C9MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090253673-A1 | Substituted Pyrazoles as Ghrelin Receptor Antagonists | MERCK SHARP & DOHME CORP. | 2009-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253673-A1 | Substituted Pyrazoles as Ghrelin Receptor Antagonists | GIPR, GPR119, GLP1R | ALDH1A1 3415/4885TSHR 70/4885CYP2C9 2168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.