SCHEMBL13664629

SCHEMBL13664629

C=C(F)C(=O)OCOc1ccc(C(=O)Oc2ccc(OC(=O)c3ccc(OCOC(=O)C(=C)F)cc3)c(C(F)(F)F)c2C(F)(F)F)cc1

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.34
PRSS1 P07477 1/20 0.33
ACR P10323 1/20 0.33
MAPT P10636 2/20 0.33
KMT2A Q03164 2/20 0.33
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
PPARD Q03181 1/20 0.32
TDP1 Q9NUW8 2/20 0.32
POLB P06746 1/20 0.32
APEX1 P27695 1/20 0.32
HTT P42858 1/20 0.32
CCNC P24863 1/20 0.31
CDK8 P49336 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13664635 0.96 MAOB (0.33) MAOBPRSS1ACRMAPTKMT2A
SCHEMBL14088593 0.87 HTT (0.47) MAPTKMT2ANPC1SMN1; SMN2TDP1
SCHEMBL13664640 0.84 FFAR1 (0.35) KMT2APPARD
SCHEMBL13664634 0.83 KMT2A (0.42) PRSS1ACRMAPTKMT2ANPC1
SCHEMBL12154225 0.83 THRB (0.38) MAOBPRSS1ACRMAPTKMT2A
SCHEMBL11986168 0.81 MAPT (0.38) MAPTKMT2APPARDTDP1POLB
SCHEMBL13664646 0.81 PPARD (0.39) MAPTKMT2APPARDTDP1
SCHEMBL12731125 0.80 THRB (0.36) MAOBPRSS1ACRMAPTKMT2A
SCHEMBL13107519 0.79 TDP1 (0.51) MAOBMAPTKMT2ANPC1RAB9A
SCHEMBL13664631 0.78 KMT2A (0.39) MAPTKMT2ANPC1PPARDTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7597945-B2 Optical compensation film; mixture of three (meth)acrylate monomers: e.g. 2,7-bis(acryloyloxyhexyloxy-1,4-phenylenecarbonyloxy)fluorene, a bis 2-fluoroacrylate monomer, and a cyanobiphenyloxyalkanol ester of (meth)acrylic acid; hardness, heat resistance, weatherability, colorless, LC physical properties CHISSO CORPORATION (JP) 2009-10-06 US disclosed
US-7597945-B2 Optical compensation film; mixture of three (meth)acrylate monomers: e.g. 2,7-bis(acryloyloxyhexyloxy-1,4-phenylenecarbonyloxy)fluorene, a bis 2-fluoroacrylate monomer, and a cyanobiphenyloxyalkanol ester of (meth)acrylic acid; hardness, heat resistance, weatherability, colorless, LC physical properties CHISSO CORPORATION (JP) 2009-10-06 US disclosed