SCHEMBL13664637

SCHEMBL13664637

C=C(F)C(=O)OCOc1ccc(COc2ccc(OCc3ccc(OCOC(=O)C(=C)F)cc3)c(C)c2)cc1

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 13/20 0.44
PPARG P37231 1/20 0.44
FFAR4 Q5NUL3 2/20 0.43
PPARA Q07869 2/20 0.42
FFAR1 O14842 2/20 0.40
MAOB P27338 2/20 0.39
PARP10 Q53GL7 1/20 0.39
HRH3 Q9Y5N1 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13664646 0.82 PPARD (0.39) PPARDPPARGPPARA
SCHEMBL13664633 0.82 FFAR1 (0.47) FFAR4FFAR1MAOBPARP10
SCHEMBL11986168 0.80 MAPT (0.38) PPARD
SCHEMBL13664631 0.79 KMT2A (0.39) PPARDPPARGPPARA
SCHEMBL13664643 0.74 KMT2A (0.47) MAOB
SCHEMBL18636228 0.73 MAOB (0.56) PPARDPPARGMAOBPARP10
SCHEMBL21266140 0.71 THRB (0.39) PPARDPPARGFFAR4PPARAFFAR1
SCHEMBL1439758 0.70 PPARD (0.58) PPARDPPARGFFAR4FFAR1MAOB
SCHEMBL12733732 0.69 KMT2A (0.35) PPARD
SCHEMBL11986094 0.69 POLB (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7597945-B2 Optical compensation film; mixture of three (meth)acrylate monomers: e.g. 2,7-bis(acryloyloxyhexyloxy-1,4-phenylenecarbonyloxy)fluorene, a bis 2-fluoroacrylate monomer, and a cyanobiphenyloxyalkanol ester of (meth)acrylic acid; hardness, heat resistance, weatherability, colorless, LC physical properties CHISSO CORPORATION (JP) 2009-10-06 US disclosed
US-7597945-B2 Optical compensation film; mixture of three (meth)acrylate monomers: e.g. 2,7-bis(acryloyloxyhexyloxy-1,4-phenylenecarbonyloxy)fluorene, a bis 2-fluoroacrylate monomer, and a cyanobiphenyloxyalkanol ester of (meth)acrylic acid; hardness, heat resistance, weatherability, colorless, LC physical properties CHISSO CORPORATION (JP) 2009-10-06 US disclosed