Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.64 |
| ▸ | SCN4A | P35499 | 1/20 | 0.64 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.64 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.44 |
| ▸ | MASP2 | O00187 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13655248 | 0.81 | SCN4A (0.62) | SCN9ASCN4ASCN3AMAPTALDH1A1 | |
| SCHEMBL20501030 | 0.80 | SCN9A (0.61) | SCN9ASCN4ASCN3ASCN5AMASP2 | |
| SCHEMBL20501076 | 0.79 | SCN9A (0.61) | SCN9ASCN4ASCN3AMASP2MAPT | |
| SCHEMBL28368753 | 0.79 | SCN9A (0.60) | SCN9ASCN4ASCN3ASCN5AMASP2 | |
| SCHEMBL13655269 | 0.76 | SCN9A (0.59) | SCN9ASCN4ASCN3ASCN5AMASP2 | |
| SCHEMBL13655257 | 0.76 | MAPT (0.58) | SCN9ASCN4ASCN3AMAPTALDH1A1 | |
| SCHEMBL13655093 | 0.76 | SCN4A (0.58) | SCN9ASCN4ASCN3AMAPTTP53 | |
| SCHEMBL20501157 | 0.76 | SCN9A (0.57) | SCN9ASCN4ASCN3AMASP2 | |
| SCHEMBL20501016 | 0.74 | SCN9A (0.55) | SCN9ASCN4ASCN3ASCN5AMASP2 | |
| SCHEMBL20500943 | 0.74 | SCN9A (0.55) | SCN9ASCN4ASCN3AMASP2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090270475-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-PHENYL DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270475-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-PHENYL DERIVATIVES | TFPI, O60361, PGLS | SCN9A 2854/4885SCN4A 4192/4885SCN3A 3773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.