Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 3/20 | 0.61 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.61 |
| ▸ | SCN4A | P35499 | 1/20 | 0.61 |
| ▸ | MASP2 | O00187 | 1/20 | 0.53 |
| ▸ | MGLL | Q99685 | 1/20 | 0.51 |
| ▸ | DDX3X | O00571 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 6/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | PRKACA | P17612 | 1/20 | 0.45 |
| ▸ | LTK | P29376 | 1/20 | 0.45 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.45 |
| ▸ | CDK8 | P49336 | 1/20 | 0.45 |
| ▸ | CLK2 | P49760 | 1/20 | 0.45 |
| ▸ | PRKX | P51817 | 1/20 | 0.45 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20501076 | 0.96 | SCN9A (0.61) | SCN9ASCN3ASCN4AMASP2MGLL | |
| SCHEMBL20501157 | 0.95 | SCN9A (0.57) | SCN9ASCN3ASCN4AMASP2MGLL | |
| SCHEMBL20500943 | 0.92 | SCN9A (0.55) | SCN9ASCN3ASCN4AMASP2MGLL | |
| SCHEMBL20501016 | 0.92 | SCN9A (0.55) | SCN9ASCN3ASCN4AMASP2MGLL | |
| SCHEMBL20501025 | 0.91 | SCN4A (0.54) | SCN9ASCN3ASCN4ACNR1IGF1R | |
| SCHEMBL20501013 | 0.91 | CNR1 (0.61) | SCN9ASCN3ASCN4ACNR1CNR2 | |
| SCHEMBL20501039 | 0.91 | KDR (0.54) | SCN9ASCN3ASCN4ACNR1CDK8 | |
| SCHEMBL20500996 | 0.90 | SCN9A (0.53) | SCN9ASCN3ASCN4AMASP2CNR1 | |
| SCHEMBL20500985 | 0.90 | SCN9A (0.53) | SCN9ASCN3ASCN4AMASP2MGLL | |
| SCHEMBL20500967 | 0.90 | SCN9A (0.53) | SCN9ASCN3ASCN4AMASP2MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11582970-B2 | 2-aminoimidazole-phenyl derivatives useful for controlling microbial growth | NORTH CAROLINA STATE UNIVERSITY (US) | 2023-02-21 | — | — | US | disclosed |
| US-20220000118-A1 | 2-AMINOIMIDAZOLE-PHENYL DERIVATIVES USEFUL FOR CONTROLLING MICROBIAL GROWTH | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2022-01-06 | — | — | US | disclosed |
| WO-2018169752-A1 | 2-AMINOIMIDAZOLE-PHENYL DERIVATIVES USEFUL FOR CONTROLLING MICROBIAL GROWTH | NORTH CAROLINA STATE UNIVERSITY (US) | 2018-09-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11582970-B2 | 2-aminoimidazole-phenyl derivatives useful for controlling microbial growth | DDC, IL4I1, ING2 | SCN9A 4811/4885SCN3A 4795/4885SCN4A 4688/4885 |
| US-20220000118-A1 | 2-AMINOIMIDAZOLE-PHENYL DERIVATIVES USEFUL FOR CONTROLLING MICROBIAL GROWTH | DDC, IL4I1, ING2 | SCN9A 4811/4885SCN3A 4795/4885SCN4A 4688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.