Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 5/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 4/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.37 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.37 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.37 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13664728 | 0.77 | BACE1 (0.43) | HDAC3HDAC1HDAC2NCOR2LMNA | |
| SCHEMBL28466070 | 0.75 | HDAC1 (0.51) | HDAC3HDAC1HDAC2NCOR2MEN1 | |
| SCHEMBL28910079 | 0.73 | ALDH1A1 (0.46) | HDAC3HDAC1HDAC2NCOR2ALDH1A1 | |
| SCHEMBL28910076 | 0.73 | ALDH1A1 (0.46) | HDAC3HDAC1HDAC2NCOR2ALDH1A1 | |
| SCHEMBL5122254 | 0.70 | HDAC3 (0.51) | HDAC3HDAC1HDAC2NCOR2ALDH1A1 | |
| SCHEMBL757279 | 0.70 | HDAC1 (0.48) | HDAC3HDAC1HDAC2NCOR2LMNA | |
| SCHEMBL13617413 | 0.69 | HDAC3 (0.53) | HDAC3HDAC1HDAC2NCOR2NPC1 | |
| SCHEMBL5234651 | 0.69 | MT-CO2 (0.35) | LMNAHTTNPSR1MAPTMEN1 | |
| SCHEMBL9823156 | 0.69 | HDAC1 (0.54) | HDAC3HDAC1HDAC2NCOR2NPC1 | |
| SCHEMBL9060170 | 0.69 | HDAC1 (0.60) | HDAC3HDAC1HDAC2NCOR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119528-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |