Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 11/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.59 |
| ▸ | CTSG | P08311 | 2/20 | 0.42 |
| ▸ | CMA1 | P23946 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | BID | P55957 | 1/20 | 0.39 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.39 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13664798 | 0.76 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3MAPTALDH1A1 | |
| SCHEMBL13665268 | 0.75 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3CTSGCMA1 | |
| SCHEMBL13664676 | 0.69 | SLC6A2 (0.60) | SLC6A2SLC6A4SLC6A3NPC1RAB9A | |
| SCHEMBL13664856 | 0.67 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3CTSGCMA1 | |
| SCHEMBL13664866 | 0.66 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3MAPTALDH1A1 | |
| SCHEMBL9819272 | 0.66 | SLC6A2 (0.56) | SLC6A2SLC6A4SLC6A3CTSGCMA1 | |
| SCHEMBL11817169 | 0.65 | SLC6A2 (0.59) | SLC6A2SLC6A4SLC6A3CTSGCMA1 | |
| SCHEMBL6028720 | 0.64 | KMT2A (0.53) | SLC6A2SLC6A4CTSGCMA1MEN1 | |
| SCHEMBL1779650 | 0.64 | ADRB1 (0.53) | SLC6A2SLC6A4MEN1KMT2AHTR1A | |
| SCHEMBL9078206 | 0.64 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119528-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |