Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.48 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | GPR183 | P32249 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13664725 | 0.88 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3USP30MAPT | |
| SCHEMBL13664866 | 0.87 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3USP30MAPT | |
| SCHEMBL13664724 | 0.79 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3MAPTSMN1; SMN2 | |
| SCHEMBL13664689 | 0.79 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3USP30MAPT | |
| SCHEMBL25216200 | 0.78 | MAPT (0.50) | MAPTSMN1; SMN2MAPK1HTTALDH1A1 | |
| SCHEMBL13664718 | 0.76 | SLC6A2 (0.60) | SLC6A2SLC6A4SLC6A3MAPTALDH1A1 | |
| SCHEMBL13664691 | 0.75 | MAPT (0.50) | SLC6A2SLC6A4SLC6A3MAPTSMN1; SMN2 | |
| SCHEMBL26629245 | 0.74 | NR1H2 (0.46) | SLC6A2SLC6A4MAPTSMN1; SMN2HTT | |
| SCHEMBL13664818 | 0.73 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3MAPTSMN1; SMN2 | |
| SCHEMBL13664895 | 0.72 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119528-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |