Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 3/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13664796 | 0.75 | MEN1 (0.40) | EGFRAURKBLMNASMN1; SMN2TSHR | |
| SCHEMBL17336558 | 0.72 | ALDH1A1 (0.41) | LMNASMN1; SMN2TSHRIDO1MCHR1 | |
| SCHEMBL13664697 | 0.71 | TDP1 (0.42) | LMNASMN1; SMN2IDO1ALDH1A1NPC1 | |
| SCHEMBL29498076 | 0.68 | S1PR3 (0.39) | LMNASMN1; SMN2TSHRIDO1ALDH1A1 | |
| SCHEMBL29498068 | 0.68 | S1PR3 (0.39) | LMNASMN1; SMN2TSHRIDO1ALDH1A1 | |
| SCHEMBL29570197 | 0.68 | S1PR3 (0.39) | LMNASMN1; SMN2TSHRIDO1ALDH1A1 | |
| SCHEMBL13665283 | 0.67 | MAPK3 (0.39) | LMNAIDO1KMT2AMEN1MAPK3 | |
| SCHEMBL19932072 | 0.66 | EGFR (0.57) | EGFRAURKBLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL13664868 | 0.66 | STK17B (0.55) | LMNAIDO1KMT2AMEN1MAPT | |
| SCHEMBL13664819 | 0.66 | STK17B (0.52) | LMNAIDO1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119528-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |