Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | FLT1 | P17948 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12378577 | 0.86 | ALDH1A1 (0.43) | ALDH1A1TDP1KDM1AKDM1BMAPT | |
| SCHEMBL926241 | 0.86 | ALDH1A1 (0.43) | ALDH1A1TDP1KDM1AKDM1BMAPT | |
| SCHEMBL30525059 | 0.86 | ALDH1A1 (0.43) | ALDH1A1TDP1KDM1AKDM1BMAPT | |
| SCHEMBL12479245 | 0.80 | ALDH1A1 (0.43) | ALDH1A1TDP1KDM1AKDM1BMAPT | |
| SCHEMBL22289792 | 0.79 | AHR (0.39) | ALDH1A1TDP1AHRKDM1AKDM1B | |
| SCHEMBL21834381 | 0.79 | GAA (0.50) | ALDH1A1TDP1MAPK1KDM1AKDM1B | |
| SCHEMBL22289313 | 0.79 | AHR (0.39) | ALDH1A1TDP1AHRKDM1AKDM1B | |
| SCHEMBL29503648 | 0.79 | AHR (0.39) | ALDH1A1TDP1AHRKDM1AKDM1B | |
| SCHEMBL7665669 | 0.79 | TSHR (0.46) | ALDH1A1TDP1ACHEBACE1 | |
| SCHEMBL832773 | 0.79 | CD44 (0.41) | ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119528-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |