SCHEMBL7665669

SCHEMBL7665669

Oc1cc(I)c(F)cc1Cl

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.46
HSD17B10 Q99714 5/20 0.46
HPGD P15428 3/20 0.46
ALDH1A1 P00352 3/20 0.36
CYP3A4 P08684 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
ACHE P22303 1/20 0.33
BACE1 P56817 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
ESR2 Q92731 2/20 0.33
ESR1 P03372 1/20 0.33
HSP90AA1 P07900 1/20 0.32
HSD17B1 P14061 1/20 0.32
HSD17B2 P37059 1/20 0.32
ADRA1A P35348 1/20 0.31
CA3 P07451 1/20 0.31
CA6 P23280 1/20 0.31
CA5A P35218 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9386078 0.88 HPGD (0.37) TSHRHSD17B10HPGDALDH1A1CA1
SCHEMBL18893969 0.79 HSD17B10 (0.55) TSHRHSD17B10HPGDALDH1A1CYP3A4
SCHEMBL13664729 0.79 ALDH1A1 (0.34) ALDH1A1TDP1ACHEBACE1
SCHEMBL30525059 0.77 ALDH1A1 (0.43) ALDH1A1TDP1
SCHEMBL926241 0.77 ALDH1A1 (0.43) ALDH1A1TDP1
SCHEMBL911775 0.77 TSHR (0.60) TSHRHSD17B10HPGDALDH1A1CYP3A4
SCHEMBL31357885 0.77 TSHR (0.60) TSHRHSD17B10HPGDALDH1A1CYP3A4
SCHEMBL1425452 0.77 HSD17B10 (0.60) TSHRHSD17B10HPGDALDH1A1CYP3A4
SCHEMBL21614392 0.77 CA3 (0.40) ACHEBACE1CA1CA2ESR2
SCHEMBL30209352 0.77 CA3 (0.40) ACHEBACE1CA1CA2ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12133529-B2 Herbicidal phenylethers BASF SE (DE) 2024-11-05 US disclosed
US-20230345941-A1 HERBICIDAL PHENYLETHERS BASF SE (DE) 2023-11-02 US disclosed
US-20200305429-A1 HERBICIDAL PHENYLETHERS BASF SE (DE) 2020-10-01 US disclosed
CN-111356693-A Herbicidal phenyl ethers 巴斯夫欧洲公司 2020-06-30 CN disclosed
WO-2019101551-A1 HERBICIDAL PHENYLETHERS BASF SE (DE) 2019-05-31 WO disclosed
WO-2019101551-A1 HERBICIDAL PHENYLETHERS BASF SE (DE) 2019-05-31 WO disclosed
US-6358885-B1 PREEMERGENT OR POSTEMERGENT HERBICIDES OR PLANT GROWTH REGULANTS MISSISSIPPI STATE UNIVERSITY 2002-03-19 US disclosed
US-5977028-A Substituted phenylheterocyclic herbicides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1999-11-02 US disclosed
EP-0626962-B1 SUBSTITUTED PHENYLHETEROCYCLIC HERBICIDES DU PONT (US) 1999-03-17 EP disclosed
US-5670455-A Substituted phenylheterocyclic herbicides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1997-09-23 US disclosed
WO-1993015074-A1 SUBSTITUTED PHENYLHETEROCYCLIC HERBICIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-08-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200305429-A1 HERBICIDAL PHENYLETHERS DDT, HPD, GSTM2 TSHR 3222/4885HSD17B10 110/4885HPGD 1220/4885
US-12133529-B2 Herbicidal phenylethers DDT, HPD, GSTM2 TSHR 3222/4885HSD17B10 110/4885HPGD 1220/4885
US-20230345941-A1 HERBICIDAL PHENYLETHERS DDT, HPD, GSTM2 TSHR 3222/4885HSD17B10 110/4885HPGD 1220/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.