Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 5/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1616769 | 0.77 | TLR4 (0.42) | MAPTMEN1KMT2A | |
| SCHEMBL13664743 | 0.74 | TP53 (0.42) | ADRB1HTR2AHTR2CHTR2BSLC6A2 | |
| SCHEMBL373671 | 0.71 | SLC18A3 (0.50) | GABRA1GABRG2GABRB3CHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL19695359 | 0.70 | SLC18A3 (0.48) | GABRA1GABRG2GABRB3CHRM2CHRM4 | |
| SCHEMBL18616622 | 0.69 | SLC6A3 (0.43) | GABRA1GABRG2GABRB3ADRB1HTR2A | |
| SCHEMBL829002 | 0.64 | HTR3A (0.66) | HTR2AHTR2BHTR6HTR3ASLC6A2 | |
| SCHEMBL826278 | 0.64 | HTR3A (0.66) | HTR2AHTR2BHTR6HTR3ASLC6A2 | |
| SCHEMBL826297 | 0.64 | HTR3A (0.66) | HTR2AHTR2BHTR6HTR3ASLC6A2 | |
| SCHEMBL14337203 | 0.62 | ESR2 (0.48) | GABRA1GABRG2GABRB3MEN1KMT2A | |
| SCHEMBL15282087 | 0.62 | SRD5A1 (0.43) | HTR3ATHRBSLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119528-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |