Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4885246 | 0.82 | ACHE (0.44) | ACHEATMHTTOPRK1RECQL | |
| SCHEMBL19132946 | 0.82 | XDH (0.45) | ACHEATMHTTOPRK1RECQL | |
| SCHEMBL14970282 | 0.78 | HPGD (0.51) | ACHEATMALDH1A1KDM4EHPGD | |
| SCHEMBL14965967 | 0.78 | HPGD (0.51) | ACHEATMALDH1A1KDM4EHPGD | |
| SCHEMBL2186672 | 0.77 | MEN1 (0.49) | ACHEALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL16870307 | 0.73 | POLL (0.43) | HTTALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL13925623 | 0.73 | ACHE (0.61) | ACHEATMALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL16210208 | 0.70 | KDM4E (0.44) | ACHEOPRK1ALDH1A1KDM4EHPGD | |
| SCHEMBL14965915 | 0.70 | KDM4E (0.44) | ALDH1A1KDM4EHPGDMAPTSMN1; SMN2 | |
| SCHEMBL16209393 | 0.70 | KDM4E (0.44) | ALDH1A1KDM4EHPGDMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119858-A1 | BENZENE COMPOUND, AND USE THEREOF FOR MEDICAL PURPOSES | 田辺三菱製薬株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |