Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3614196 | 0.78 | MAOA (0.56) | MAOAMAOBTAAR1OPRM1OPRL1 | |
| SCHEMBL17700462 | 0.75 | ALDH1A1 (0.41) | CA2AOC3MAOAMAOBOPRM1 | |
| SCHEMBL17700363 | 0.73 | ALDH1A1 (0.45) | CA2AOC3OPRM1OPRL1ALDH1A1 | |
| SCHEMBL9245361 | 0.71 | MAOA (0.52) | MAOAMAOBTAAR1OPRM1OPRL1 | |
| SCHEMBL9141601 | 0.71 | MAOA (0.52) | MAOAMAOBTAAR1OPRM1OPRL1 | |
| SCHEMBL5694869 | 0.71 | HTR2A (0.48) | MAOAMAOBTAAR1OPRM1OPRL1 | |
| SCHEMBL16155087 | 0.71 | AOC3 (0.52) | CA2AOC3CARM1PRMT6PRMT8 | |
| SCHEMBL25663631 | 0.70 | OPRL1 (0.38) | CA2OPRM1OPRL1ALDH1A1TSHR | |
| SCHEMBL5447122 | 0.70 | HDAC3 (0.39) | OPRM1OPRL1HDAC3HDAC1HDAC2 | |
| SCHEMBL134524 | 0.70 | TSHR (0.60) | CA2AOC3CARM1PRMT6PRMT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119528-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |