Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 18/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 12/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | NSD2 | O96028 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 10/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13664590 | 0.93 | KDM4E (0.69) | KDM4EHSD17B10ALDH1A1LMNANSD2 | |
| SCHEMBL13664755 | 0.90 | KDM4E (0.65) | KDM4EHSD17B10ALDH1A1LMNANSD2 | |
| SCHEMBL13664845 | 0.86 | KDM4E (0.66) | KDM4EHSD17B10ALDH1A1LMNANSD2 | |
| SCHEMBL13664838 | 0.86 | KDM4E (0.70) | KDM4EHSD17B10ALDH1A1LMNANSD2 | |
| SCHEMBL13496398 | 0.73 | KDM4E (0.77) | KDM4EHSD17B10ALDH1A1LMNANSD2 | |
| SCHEMBL4079416 | 0.73 | KDM4E (0.84) | KDM4EHSD17B10ALDH1A1LMNANSD2 | |
| SCHEMBL13664758 | 0.71 | TSHR (0.65) | KDM4EHSD17B10ALDH1A1POLBHPGD | |
| SCHEMBL13664567 | 0.70 | KDM4E (0.58) | KDM4EHSD17B10ALDH1A1LMNANSD2 | |
| SCHEMBL4072881 | 0.69 | MAPT (0.72) | KDM4EHSD17B10ALDH1A1LMNANSD2 | |
| SCHEMBL30307323 | 0.69 | ALDH1A1 (0.70) | KDM4EHSD17B10ALDH1A1LMNANSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009128262-A1 | QUINOLONE DERIVATIVE AND USE THEREOF | 武田薬品工業株式会社 (JP) | 2009-10-22 | — | — | WO | disclosed |