Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.62 |
| ▸ | HPGD | P15428 | 7/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13665093 | 0.89 | TSHR (0.61) | TSHRKDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL13664756 | 0.85 | TSHR (0.64) | TSHRKDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL15270604 | 0.78 | HDAC1 (0.72) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL18424429 | 0.74 | KDM4E (0.78) | TSHRKDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL13664838 | 0.72 | KDM4E (0.70) | KDM4EHSD17B10ALDH1A1HPGDMAPT | |
| SCHEMBL13664590 | 0.71 | KDM4E (0.69) | KDM4EHSD17B10ALDH1A1HPGDMAPT | |
| SCHEMBL13664841 | 0.71 | KDM4E (0.68) | KDM4EHSD17B10ALDH1A1HPGDMAPT | |
| SCHEMBL13664845 | 0.70 | KDM4E (0.66) | TSHRKDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL4250505 | 0.69 | ALDH1A1 (0.78) | KDM4EHSD17B10ALDH1A1HPGDMAPT | |
| SCHEMBL978722 | 0.68 | F2 (0.62) | KDM4EHPGDMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009128262-A1 | QUINOLONE DERIVATIVE AND USE THEREOF | 武田薬品工業株式会社 (JP) | 2009-10-22 | — | — | WO | disclosed |