Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13665427 | 0.96 | RAB9A (0.47) | NPC1RAB9AGAAPOLBMCL1 | |
| SCHEMBL13665235 | 0.88 | NR1H4 (0.53) | NPC1RAB9AGAAPOLBMAPT | |
| SCHEMBL4658142 | 0.86 | RAB9A (0.60) | NPC1RAB9AHDAC1HDAC2PDE4A | |
| SCHEMBL4658325 | 0.84 | FFAR1 (0.57) | NPC1RAB9AGAAMCL1BCL2A1 | |
| SCHEMBL4657977 | 0.84 | FFAR1 (0.57) | NPC1RAB9AGAAMCL1BCL2A1 | |
| SCHEMBL4658315 | 0.83 | FFAR1 (0.58) | NPC1RAB9AGAAMCL1BCL2A1 | |
| SCHEMBL13665224 | 0.82 | FFAR1 (0.59) | MAPTS1PR1S1PR3S1PR5 | |
| SCHEMBL13664800 | 0.80 | S1PR1 (0.50) | GAAPOLBPDE4APDE4BPDE4C | |
| SCHEMBL13665328 | 0.80 | ALDH1A1 (0.48) | NPC1RAB9AGAAPOLBHDAC1 | |
| SCHEMBL4657080 | 0.78 | RAB9A (0.57) | NPC1RAB9AHDAC1HDAC2PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119858-A1 | BENZENE COMPOUND, AND USE THEREOF FOR MEDICAL PURPOSES | 田辺三菱製薬株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |