Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25590733 | 0.86 | MAPT (0.46) | MAPTMEN1KMT2AATML3MBTL1 | |
| SCHEMBL10888418 | 0.82 | PNMT (0.50) | PNMTMAPTMEN1KMT2AATM | |
| SCHEMBL10893197 | 0.77 | MEN1 (0.45) | MAPTMEN1KMT2AATML3MBTL1 | |
| SCHEMBL3056107 | 0.76 | MAPT (0.54) | PNMTMAPTMEN1KMT2AATM | |
| SCHEMBL3393682 | 0.76 | ABL1 (0.53) | MAPTMEN1KMT2AATML3MBTL1 | |
| SCHEMBL13664887 | 0.75 | KCNH2 (0.41) | MAPTMEN1KMT2AATML3MBTL1 | |
| SCHEMBL1565326 | 0.74 | HPGD (0.49) | PNMTMAPTMEN1KMT2AATM | |
| Hydrochloric Acid SCHEMBL3398835 | 0.74 | ABL1 (0.51) | MAPTMEN1KMT2AATML3MBTL1 | |
| SCHEMBL10888882 | 0.74 | MEN1 (0.51) | MAPTMEN1KMT2AATML3MBTL1 | |
| SCHEMBL6950384 | 0.73 | ABL1 (0.63) | MAPTMEN1KMT2AATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119528-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |