Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13664860 | 0.80 | MMP8 (0.41) | KCNH2TMEM97MEN1KMT2AMAPT | |
| SCHEMBL25590733 | 0.78 | MAPT (0.46) | KCNH2GRIN1GRIN2BMEN1KMT2A | |
| SCHEMBL13665269 | 0.75 | CYP3A4 (0.39) | KCNH2GRIN1GRIN2BMEN1KMT2A | |
| SCHEMBL13664864 | 0.75 | PNMT (0.47) | KCNH2GRIN1GRIN2BMEN1KMT2A | |
| SCHEMBL10893197 | 0.73 | MEN1 (0.45) | KCNH2GRIN1GRIN2BMEN1KMT2A | |
| SCHEMBL13665284 | 0.71 | AAK1 (0.43) | GRIN1GRIN2BMEN1KMT2AMAPT | |
| SCHEMBL13664675 | 0.70 | GRIN1 (0.43) | KCNH2GRIN1GRIN2BMEN1KMT2A | |
| SCHEMBL13664855 | 0.70 | POLB (0.40) | KCNH2GRIN1GRIN2BMEN1KMT2A | |
| SCHEMBL3393682 | 0.69 | ABL1 (0.53) | KCNH2GRIN1GRIN2BMEN1KMT2A | |
| SCHEMBL9594625 | 0.68 | GRIN1 (0.51) | KCNH2GRIN1GRIN2BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119528-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |