Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 13/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 10/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 8/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CASP2 | P42575 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1679985 | 1.00 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2HDAC6HDAC1HDAC8 | |
| SCHEMBL930344 | 0.93 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2HDAC6HDAC1HDAC8 | |
| SCHEMBL15057947 | 0.91 | HDAC6 (0.54) | ALDH1A1SMN1; SMN2HDAC6HDAC1HDAC8 | |
| SCHEMBL929131 | 0.90 | HDAC6 (0.49) | ALDH1A1SMN1; SMN2HDAC6HDAC1HDAC8 | |
| SCHEMBL25885399 | 0.89 | HDAC6 (0.49) | ALDH1A1SMN1; SMN2HDAC6HDAC1HDAC8 | |
| SCHEMBL8293928 | 0.89 | HDAC6 (0.49) | ALDH1A1SMN1; SMN2HDAC6HDAC1HDAC8 | |
| SCHEMBL2802038 | 0.89 | PAOX (0.57) | ALDH1A1SMN1; SMN2HDAC6HDAC1HDAC8 | |
| SCHEMBL7564045 | 0.89 | CASP2 (0.67) | MEN1KMT2ACASP2NAAA | |
| SCHEMBL5144140 | 0.89 | CASP2 (0.67) | MEN1KMT2ACASP2NAAA | |
| SCHEMBL7564056 | 0.89 | CASP2 (0.67) | MEN1KMT2ACASP2NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110072564-A | As silane coupling agent for adhesiveness improvement comprising mercaptan, alkene and containing the composition of phosphinic acid compounds | 生物医学键合有限公司 | 2019-07-30 | — | — | CN | disclosed |
| EP-2258677-B1 | HISTONE DEACETYLASE INHIBITORS | UNIV GEORGETOWN (US) | 2014-06-18 | — | — | EP | disclosed |
| US-8067600-B2 | Histone deacetylase inhibitors and methods of use thereof | GEORGETOWN UNIVERSITY (US) | 2011-11-29 | — | — | US | disclosed |
| US-8067600-B2 | Histone deacetylase inhibitors and methods of use thereof | GEORGETOWN UNIVERSITY (US) | 2011-11-29 | — | — | US | disclosed |
| US-8067600-B2 | Histone deacetylase inhibitors and methods of use thereof | GEORGETOWN UNIVERSITY (US) | 2011-11-29 | — | — | US | disclosed |
| EP-2258677-A2 | Histone deacetylase inhibitors and methods of use thereof | GEORGETOWN UNIVERSITY (US) | 2010-12-08 | — | — | EP | disclosed |
| US-20100102975-A1 | BATTERY LEAKAGE DETECTION SYSTEM | SONY DEUTSCHLAND GMBH (DE) | 2010-04-29 | — | — | US | disclosed |
| US-20090163543-A1 | Histone Deacetylase Inhibitors and Methods of Use Thereof | GEORGETOWN UNIVERSITY (US) | 2009-06-25 | — | — | US | disclosed |
| EP-1841002-B1 | Battery leakage detection system | SONY DEUTSCHLAND GMBH (DE) | 2009-05-20 | — | — | EP | disclosed |
| US-7507828-B2 | Histone deacetylase inhibitors and methods of use thereof | GEORGETOWN UNIVERSITY (US) | 2009-03-24 | — | — | US | disclosed |
| US-7507828-B2 | Histone deacetylase inhibitors and methods of use thereof | GEORGETOWN UNIVERSITY (US) | 2009-03-24 | — | — | US | disclosed |
| US-7507828-B2 | Histone deacetylase inhibitors and methods of use thereof | GEORGETOWN UNIVERSITY (US) | 2009-03-24 | — | — | US | disclosed |
| US-20070229294-A1 | BATTERY LEAKAGE DETECTION SYSTEM | SONY DEUTSCHLAND GMBH (DE) | 2007-10-04 | — | — | US | disclosed |
| CN-101048503-A | Gonadotropin derived from invertebrate and preparation method thereof | KEK HIGH ENERGY ACCELERATOR (JP) | 2007-10-03 | — | — | CN | disclosed |
| EP-1841002-A1 | Battery leakage detection system | SONY DEUTSCHLAND GMBH (DE) | 2007-10-03 | — | — | EP | disclosed |
| EP-1644323-A4 | HISTONE DEACETYLASE INHIBITORS AND METHODS OF USE THEREOF | UNIV GEORGETOWN (US) | 2007-06-20 | — | — | EP | disclosed |
| EP-1644323-A2 | HISTONE DEACETYLASE INHIBITORS AND METHODS OF USE THEREOF | GEORGETOWN UNIVERSITY (US) | 2006-04-12 | — | — | EP | disclosed |
| US-20050032831-A1 | Histone deacetylase inhibitors and methods of use thereof | GEORGETOWN UNIVERSITY | 2005-02-10 | — | — | US | disclosed |
| WO-2005007091-A2 | HISTONE DEACETYLASE INHIBITORS AND METHODS OF USE THEREOF | GEORGETOWN UNIVERSITY (US) | 2005-01-27 | — | — | WO | disclosed |
| WO-2005007091-A2 | HISTONE DEACETYLASE INHIBITORS AND METHODS OF USE THEREOF | GEORGETOWN UNIVERSITY (US) | 2005-01-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163543-A1 | Histone Deacetylase Inhibitors and Methods of Use Thereof | HDAC5, HDAC6, HDAC1 | ALDH1A1 376/4885SMN1; SMN2 855/4885HDAC6 2/4885 |
| US-20050032831-A1 | Histone deacetylase inhibitors and methods of use thereof | HDAC5, HDAC6, HDAC1 | ALDH1A1 376/4885SMN1; SMN2 855/4885HDAC6 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.