⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11559288 | 0.78 | — | — | |
| SCHEMBL5493998 | 0.74 | CYP2A6 (0.40) | — | |
| SCHEMBL827343 | 0.72 | — | — | |
| SCHEMBL7593958 | 0.70 | — | — | |
| SCHEMBL11603671 | 0.68 | CYP2A6 (0.36) | — | |
| SCHEMBL3996520 | 0.68 | CYP2A6 (0.36) | — | |
| SCHEMBL14997477 | 0.67 | ALOX5 (0.35) | — | |
| SCHEMBL4582641 | 0.67 | — | — | |
| SCHEMBL31604189 | 0.65 | CYP2A6 (0.34) | — | |
| SCHEMBL9351950 | 0.65 | GSK3B (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847532-B1 | IGF-1R INHIBITOR | KYOWA HAKKO KIRIN CO LTD (JP) | 2013-06-05 | — | — | EP | disclosed |
| US-7605272-B2 | IGF-1R inhibitor | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2009-10-20 | — | — | US | disclosed |
| US-20090054508-A1 | IGF-1R INHIBITOR | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2009-02-26 | — | — | US | disclosed |