Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | PI4KA | P42356 | 1/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.32 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.31 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.30 |
| ▸ | CSF1R | P07333 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.30 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12807212 | 0.83 | AXL (0.38) | GCKPIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL13665682 | 0.83 | GCK (0.33) | GCK | |
| SCHEMBL12807184 | 0.80 | GCK (0.34) | GCKPIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL1076403 | 0.79 | IDO1 (0.39) | GCK | |
| SCHEMBL1076607 | 0.79 | IDO1 (0.35) | GCKPIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL1076900 | 0.78 | HPGD (0.44) | GCK | |
| SCHEMBL13665416 | 0.77 | GCK (0.39) | GCK | |
| SCHEMBL1677370 | 0.75 | RAB9A (0.48) | — | |
| SCHEMBL12807189 | 0.74 | GCK (0.33) | GCKPIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL13665452 | 0.74 | GCK (0.33) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009125873-A1 | FUSED RING COMPOUNDS AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-10-15 | — | — | WO | disclosed |