Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | HPGD | P15428 | 3/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL299525 | 0.88 | ALDH1A1 (0.51) | ALDH1A1HPGDSMN1; SMN2ALOX15HSD17B10 | |
| SCHEMBL11939025 | 0.86 | ALDH1A1 (0.66) | ALDH1A1HPGDSMN1; SMN2ALOX15HSD17B10 | |
| SCHEMBL12635413 | 0.86 | ALDH1A1 (0.66) | ALDH1A1HPGDSMN1; SMN2ALOX15HSD17B10 | |
| SCHEMBL1037732 | 0.82 | ALDH1A1 (0.63) | ALDH1A1HPGDSMN1; SMN2ALOX15HSD17B10 | |
| SCHEMBL14653103 | 0.77 | ALOX15 (0.84) | ALDH1A1HPGDSMN1; SMN2ALOX15HSD17B10 | |
| SCHEMBL17863709 | 0.75 | KMT2A (0.44) | ALDH1A1HPGDHSD17B10KDM4EL3MBTL1 | |
| SCHEMBL12635428 | 0.74 | ALDH1A1 (0.50) | ALDH1A1HPGDSMN1; SMN2ALOX15HSD17B10 | |
| SCHEMBL11939338 | 0.74 | ALDH1A1 (0.50) | ALDH1A1HPGDSMN1; SMN2ALOX15HSD17B10 | |
| SCHEMBL13075779 | 0.74 | KMT2A (0.46) | ALDH1A1HPGDKDM4EHTTL3MBTL1 | |
| SCHEMBL3119020 | 0.72 | ALDH1A1 (0.60) | ALDH1A1HPGDSMN1; SMN2ALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009124853-A1 | NEW RUTHENIUM COMPLEXES AS CATALYSTS FOR METATHESIS REACTIONS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-10-15 | — | — | WO | disclosed |