Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11002701 | 0.86 | ALDH1A1 (0.55) | ALDH1A1MAPTSMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL1706262 | 0.80 | MAPT (0.53) | ALDH1A1MAPTSMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL3155889 | 0.79 | ALDH1A1 (0.49) | ALDH1A1MAPTSMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL1532324 | 0.78 | ALDH1A1 (0.58) | ALDH1A1MAPTSMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL2103568 | 0.78 | MAPK1 (0.55) | ALDH1A1MAPTSMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL4496747 | 0.77 | L3MBTL1 (0.54) | ALDH1A1MAPTSMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL3922661 | 0.77 | MAPT (0.54) | ALDH1A1MAPTSMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL8751720 | 0.76 | ALDH1A1 (0.57) | ALDH1A1MAPTSMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL11517156 | 0.76 | ALDH1A1 (0.50) | ALDH1A1MAPTSMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL13666580 | 0.76 | ALDH1A1 (0.48) | ALDH1A1MAPTL3MBTL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119776-A1 | FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |