Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 6/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CBLB | Q13191 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dihydrosventrin SCHEMBL12559819 | 0.88 | CBLB (0.38) | HDAC1HDAC2HDAC3ITGB3ITGA2B | |
| Dihydrosventrin SCHEMBL1518647 | 0.87 | CBLB (0.38) | HDAC1HDAC2HDAC3ITGB3ITGA2B | |
| SCHEMBL12597864 | 0.85 | CBLB (0.38) | HDAC1HDAC2HDAC3ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL1518079 | 0.84 | CBLB (0.37) | HDAC1HDAC2HDAC3ITGB3ITGA2B | |
| SCHEMBL12597863 | 0.81 | CBLB (0.39) | HDAC1HDAC2HDAC3MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL1518082 | 0.81 | CBLB (0.39) | HDAC1HDAC2HDAC3MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL1518217 | 0.79 | CBLB (0.39) | HDAC1HDAC2HDAC3MAPTKDM4E | |
| SCHEMBL13803749 | 0.78 | HDAC1 (0.36) | HDAC1HDAC2HDAC3ITGB3ITGA2B | |
| SCHEMBL12648616 | 0.76 | HDAC1 (0.39) | HDAC1CBLB | |
| Hydrochloric Acid SCHEMBL1523923 | 0.75 | HDAC1 (0.39) | HDAC1CBLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009131654-A2 | INHIBITION AND DISPERSION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-10-29 | — | — | WO | disclosed |