Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4763798 | 0.79 | TSHR (0.40) | TSHRMEN1KMT2AUSP2ABCB11 | |
| SCHEMBL12761589 | 0.77 | TSHR (0.39) | TSHRMEN1KMT2AUSP2ABCB11 | |
| SCHEMBL19591877 | 0.74 | TSHR (0.36) | TSHRMEN1KMT2AUSP2ABCB11 | |
| SCHEMBL2478389 | 0.72 | TSHR (0.48) | TSHRMEN1KMT2AUSP2ABCB11 | |
| SCHEMBL6063978 | 0.72 | TSHR (0.48) | TSHRMEN1KMT2AUSP2ABCB11 | |
| SCHEMBL19088382 | 0.71 | ALOX15 (0.36) | TSHRMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL18583841 | 0.71 | TSHR (0.33) | TSHRMEN1KMT2A | |
| SCHEMBL17712226 | 0.71 | CA1 (0.40) | TSHRMEN1KMT2ATDP1CA12 | |
| SCHEMBL4675881 | 0.70 | TSHR (0.46) | TSHRMEN1KMT2AUSP2ABCB11 | |
| SCHEMBL4675760 | 0.70 | TSHR (0.46) | TSHRMEN1KMT2AUSP2ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009132135-A1 | 1' -SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES, INC. (US) | 2009-10-29 | — | — | WO | disclosed |