SCHEMBL4675760

SCHEMBL4675760

CC(C)OC(=O)C(C)(C)[O]

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.46
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
LMNA P02545 4/20 0.36
ADRA1A P35348 2/20 0.36
USP2 O75604 2/20 0.36
ABCB11 O95342 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
MAPT P10636 1/20 0.36
CYP2C9 P11712 1/20 0.36
ADRB3 P13945 1/20 0.36
HPGD P15428 1/20 0.36
CNR1 P21554 1/20 0.36
ACHE P22303 1/20 0.36
SLC6A2 P23975 1/20 0.36
HTR2A P28223 1/20 0.36
HTR2C P28335 1/20 0.36
MAPK1 P28482 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4678092 0.81 TSHR (0.43) TSHRMEN1KMT2ALMNAADRA1A
SCHEMBL2478389 0.80 TSHR (0.48) TSHRMEN1KMT2ALMNAADRA1A
SCHEMBL6063978 0.80 TSHR (0.48) TSHRMEN1KMT2ALMNAADRA1A
SCHEMBL448528 0.78 TSHR (0.46) TSHRMEN1KMT2ALMNAADRA1A
SCHEMBL4675881 0.78 TSHR (0.46) TSHRMEN1KMT2ALMNAADRA1A
SCHEMBL8093076 0.77 TSHR (0.40) TSHRMEN1KMT2ALMNAADRA1A
SCHEMBL131879 0.76 TSHR (0.43) TSHRMEN1KMT2ALMNAADRA1A
SCHEMBL12128600 0.76 TSHR (0.43) TSHRMEN1KMT2ALMNAADRA1A
SCHEMBL4678096 0.76 TSHR (0.43) TSHRMEN1KMT2ALMNAADRA1A
SCHEMBL454299 0.76 TSHR (0.43) TSHRMEN1KMT2ALMNAADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1095935-B1 6-Hydroxy-5,6-dihydrouracils as herbicides SUMITOMO CHEMICAL CO (JP) 2008-12-17 EP disclosed
EP-1101761-B1 Process for producing 3-phenyluracil compounds SUMITOMO CHEMICAL CO (JP) 2005-08-17 EP disclosed
US-20040043903-A1 Herbicides; applying to plants BASF AKTIENGESELLSCHAFT (DE) 2004-03-04 US disclosed
US-6410484-B1 ACTIVE MATERIAL; CONTROLLING WEEDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-06-25 US disclosed
US-6339155-B1 Process for producing 3-phenyluracil compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-01-15 US disclosed
EP-1101761-A2 Process for producing 3-phenyluracil compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-05-23 EP disclosed
EP-1095935-A1 6-Hydroxy-5,6-dihydrouracils as herbicides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-05-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040043903-A1 Herbicides; applying to plants DDT, DRD1, DRD4 TSHR 1003/4885MEN1 3968/4885KMT2A 1834/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.